Browsing by Subject "Calcein"

Now showing items 1-8 of 8

    • Dynamics of Chemotherapeutic Drug Release from Liposomes Using Low-Frequency Ultrasound 

      Ahmed, Salma Elgaili (2015-01)
      This thesis focuses on the study of liposomes; nanoparticles that can act as anticancer drug carriers, in combination with ultrasound applied as a drug trigger, with the objective of reducing the side effects caused by ...

    • Encapsulation and release of calcein from herceptin-conjugated eLiposomes 

      Zafar, Mah Noor; Pitt, William G.; Husseini, Ghaleb (Elsevier, 2024-03)
      Achieving an optimal therapeutic level is crucial in effectively eradicating cancer cells during treatment. However, conventional chemotherapy-associated systemic administration of anticancer agents leads to many side ...

    • Facile Ultrasound-Triggered Release of Calcein and Doxorubicin from Iron-Based Metal-Organic Frameworks 

      Ibrahim, Mihad; Sabouni, Rana; Husseini, Ghaleb; Karami, Abdollah; Bai, Reenu Geetha; Mukhopadhyay, Debasmita (American Scientific Publishers, 2020)
      Metal-organic frameworks (MOFs) are promising new nanocarriers with potential use in anticancer drug delivery. However, there is a scarcity of studies on the uptake and release of guest molecules associated with MOF ...

    • Investigating the Stability of eLiposomes at Elevated Temperatures 

      Husseini, Ghaleb; Pitt, William G.; Javadi, Marjan (Sage Publishing, 2014)
      eLiposomes encapsulate a perfluorocarbon nanoemulsion droplet inside a liposome. Ultrasound is then used as a trigger mechanism to vaporize the perfluorocarbon, break the liposome, and release the desired drug to the tumor ...

    • Over-Pressure Suppresses Ultrasonic-Induced Drug Uptake 

      Stringham, S. Briant; Viskovska, Maria A.; Richardson, Eric S.; Ohmine, Seiga; Husseini, Ghaleb; Murray, Byron K.; Pitt, William G. (Elseviser, 2008)
      Ultrasound (US) is used to enhance and target delivery of drugs and genes to cancer tissues. The present study further examines the role of acoustic cavitation in US-induced permeabilization of cell membranes and subsequent ...

    • Targeting Breast Cancer Using Hyaluronic Acid-Conjugated Liposomes Triggered with Ultrasound 

      Ben-Daya, Mohamed; Paul, Vinod; Awad, Nahid S.; AlSawaftah, Nour Majdi; Al-Sayah, Mohammad; Husseini, Ghaleb (American Science Publishers, 2021)
      The successful targeting of tumors can be achieved by conjugating targeting moieties to nanoparticles. These modifications allow nannocarriers to achieve greater targeting specificity through binding to specific receptors ...

    • Ultrasonically Controlled Albumin-conjugated Liposomes for Breast Cancer Therapy 

      Awad, Nahid S.; Paul, Vinod; Al-Sayah, Mohammad; Husseini, Ghaleb (Taylor and Francis Online, 2019)
      Targeted liposomes have high potentials in the specific and effective delivery of their loaded therapeutic agents to the tumor site. Once at the tumor site, it is important that these liposomes are triggered to release ...

    • Ultrasound-sensitive cRGD-modified liposomes as a novel drug delivery system 

      AlSawaftah, Nour Majdi; Paul, Vinod; Kosaji, Doua Jamal; Khabbaz, Leen; Awad, Nahid S.; Husseini, Ghaleb (Taylor & Francis, 2022)
      Targeted liposomes enable the delivery of encapsulated chemotherapeutics to tumours by targeting specific receptors overexpressed on the surfaces of cancer cells; this helps in reducing the systemic side effects associated ...