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Now showing items 11-18 of 18
Gold-Conjugated Curcumin as a Novel Therapeutic Agent against Brain-Eating Amoebae
(ACS Publications, 2020)
Balamuthia mandrillaris and Naegleria fowleri are free-living amoebae that cause infection of the central nervous system, granulomatous amoebic encephalitis (GAE) and primary amoebic meningoencephalitis (PAM), respectively. ...
Isoniazid Conjugated Magnetic Nanoparticles Loaded with Amphotericin B as a Potent Antiamoebic Agent against Acanthamoeba castellanii
(MDPI, 2020)
The pathogenic free-living amoeba, Acanthamoeba castellanii, is responsible for a rare but deadly central nervous system infection, granulomatous amoebic encephalitis and a blinding eye disease called Acanthamoeba keratitis. ...
Gut bacteria of Cuora amboinensis (turtle) produce broad-spectrum antibacterial molecules
(Nature Research, 2019)
Antimicrobial resistance is a major threat to human health, hence there is an urgent need to discover antibacterial molecule(s). Previously, we hypothesized that microbial gut flora of animals are a potential source of ...
Antiamoebic activity of plant‑based natural products and their conjugated silver nanoparticles against Acanthamoeba castellanii (ATCC 50492)
(Springer, 2020)
Acanthamoeba spp. are the causative agent of Acanthamoeba keratitis and granulomatous amoebic encephalitis (GAE). The current options to treat Acanthamoeba infections have limited success. Silver nanoparticles show ...
Novel insights into the potential role of ion transport in sensory perception in Acanthamoeba
(Springer Nature, 2019)
Background: Acanthamoeba is well known to produce a blinding keratitis and serious brain infection known as encephalitis. Effective treatment is problematic, and can continue up to a year, and even then, recurrence can ...
Novel Azoles as Antiparasitic Remedies against Brain-Eating Amoebae
(MDPI, 2020)
Balamuthia mandrillaris and Naegleria fowleri are opportunistic protozoan pathogens capable of producing infection of the central nervous system with more than 95% mortality rate. Previously, we have synthesized several ...
HBN Nanoparticle-Assisted Rapid Thermal Cycling for the Detection of Acanthamoeba
(MDPI, 2020)
Acanthamoeba are widely distributed in the environment and are known to cause blinding keratitis and brain infections with greater than 90% mortality rate. Currently, polymerase chain reaction (PCR) is a highly sensitive ...
Effects of Shape and Size of Cobalt Phosphate Nanoparticles against Acanthamoeba castellanii
(MDPI, 2019)
T4 genotype Acanthamoeba are opportunistic pathogens that cause two types of infections, including vision-threatening Acanthamoeba keratitis (AK) and a fatal brain infection known as granulomatous amoebic encephalitis ...