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Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment
(2016-01)
Chemotherapy is frequently used in cancer treatment. However, side effects associated with this type of treatment are often detrimental to the patient's health. This thesis discusses a novel approach of delivering a cytotoxic ...
Modeling and Bias-Robust Estimation of the Acoustic Release of Chemotherapeutics from Liposomes
(American Scientific Publishers, 2019)
This paper models the acoustic drug release of chemotherapeutics from liposomes using a kinetic model that accounts for systematic biases affecting the drug delivery process. An optimal stochastic filter is then proposed ...
Drug Delivery Systems Based on Polymeric Micelles and Ultrasound: A Review
(Bentham Science Publishers, 2016)
Anti-neoplastic drugs used for cancer treatment often produce damage to healthy cells, leading to severe side effects in patients undergoing chemotherapy. The encapsulation of these agents in nanoparticles reduces the ...
Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs)
(Bentham Science Publishers, 2017)
Cancer is the uncontrolled growth of cells in the body and is considered as one of the major causes of death globally. There are several cytotoxic chemotherapeutic agents used to treat cancer including methotrexate, ...
Factors Affecting the Acoustic In Vitro Release of Calcein from PEGylated Liposomes
(American Scientific Publishers, 2019)
Typical methods used in cancer treatment, including chemotherapy, are debilitating because of the various adverse side effects experienced by cancer patients. The free drug injected into the patient at given doses affects ...
Predicting the Release of Chemotherapeutics From the Core of Polymeric Micelles Using Ultrasound
(IEEE Explore, 2015)
In this paper, the estimation of acoustic drug release from micelles is addressed. The release is measured as a decrease in fluorescence once ultrasound is applied. Initially, a Kalman filter is used to fuse the drug ...
Using Lactose and Ultrasound to deliver chemotherapeutics
(2019-05)
As the number of cancer patients increase, so does the number of patients that undergo chemotherapy, as well as the suffering, caused by its side effects. To solve this adversity, an innovative form of delivering ...
Liposomal drug release using ultrasound and modeling release dynamics for model predictive controller design
(2015-06)
Chemotherapy is widely used for cancer treatment; however, it causes unwanted side effects in patients such as fatigue, weight loss, pain, hair fall and nausea. Those side effects are due to the fact that most of the ...
A Novel Cancer Treatment Platform Utilizing HER2-Immunoliposomes and Ultrasound
(2020-05)
Cancer is defined as the uncontrolled growth of cells in the body. It is one of the leading causes of death worldwide. One of the most common approaches to destroy cancer cells is via chemotherapy treatment, in which ...
Investigating and Modeling the Acoustic Release of Doxorubicin from Folate Targeted Micelles
(2012-06)
To minimize the adverse side effects of conventional chemotherapy, a targeted micellar drug carrier was investigated that retains hydrophobic drugs in its core and then releases the drug via ultrasound. This thesis reports ...