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Drug Delivery Systems Based on Polymeric Micelles and Ultrasound: A Review
(Bentham Science Publishers, 2016)
Anti-neoplastic drugs used for cancer treatment often produce damage to healthy cells, leading to severe side effects in patients undergoing chemotherapy. The encapsulation of these agents in nanoparticles reduces the ...
Optimizing the use of ultrasound to deliver chemotherapeutic agents to cancer cells from polymeric micelles
(Elsevier, 2011)
In this study, we present an artificial neural network (ANN) model that attempts to predict the dynamic release of doxorubicin (Dox) from P105 micelles under different ultrasonic power densities at 20 kHz. The goal is to ...
Degradation kinetics of stabilized Pluronic micelles under the action of ultrasound
(Elsevier, 2009)
The majority of research in the area of acoustically-activated drug delivery from stabilized micelles has been focused on the rapid release of chemotherapy drugs from the core of such nano-carriers. Previous publications ...
Investigating the acoustic release of doxorubicin from targeted micelles
(Elsevier, 2013)
The main problem associated with the administration of anti-cancer medication is that the drug is delivered throughout the body causing undesirable side effects. Therefore, it is important to synthesize drug carriers capable ...
Predicting the Release of Chemotherapeutics From the Core of Polymeric Micelles Using Ultrasound
(IEEE Explore, 2015)
In this paper, the estimation of acoustic drug release from micelles is addressed. The release is measured as a decrease in fluorescence once ultrasound is applied. Initially, a Kalman filter is used to fuse the drug ...
Recent Advances in Metal-Organic Frameworks as Anticancer Drug Delivery Systems: A Review
(Bentham, 2021)
Background: Metal-organic frameworks (MOFs), as attractive hybrid crystalline porous materials, are increasingly being investigated in biomedical applications owing to their exceptional properties, including high porosity, ...
Modeling of the In Vitro Release Kinetics of Sonosensitive Targeted Liposomes
(MDPI, 2022-12-05)
Targeted liposomes triggered by ultrasound are a promising drug delivery system as they potentially improve the clinical outcomes of chemotherapy while reducing associated side effects. In this work, a comprehensive model ...