Search
Now showing items 1-10 of 17
Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment
(2016-01)
Chemotherapy is frequently used in cancer treatment. However, side effects associated with this type of treatment are often detrimental to the patient's health. This thesis discusses a novel approach of delivering a cytotoxic ...
The Use of Transferrin and Ultrasound in Cancer Treatment
(2019-05)
Site-specific drug delivery represents an attractive approach in cancer treatment to reduce the undesirable side-effects of anticancer therapeutics and increase the accumulation of drugs at tumor sites. Surface modification ...
Using a Cavitation Model to Represent the Acoustic Release Kinetics from Folated Micelles
(2014-12)
Anti-neoplastic drugs used for cancer treatment have various damaging effects on healthy cells, leading to several side effects in patients undergoing chemotherapy. The encapsulation of these agents in nanoparticles, such ...
Ultrasound Triggered Release of Estrone- Targeted Liposomes
(2017-05)
The fight against cancer has proven to be a lengthy one. Conventional treatment of cancer usually involves chemotherapy, a therapy known for its detrimental side effects. Doxorubicin, a cytotoxic anthracycline antibiotic, ...
Drug Delivery Systems Based on Polymeric Micelles and Ultrasound: A Review
(Bentham Science Publishers, 2016)
Anti-neoplastic drugs used for cancer treatment often produce damage to healthy cells, leading to severe side effects in patients undergoing chemotherapy. The encapsulation of these agents in nanoparticles reduces the ...
Multi-Model Investigation and Adaptive Estimation of the Acoustic Release of a Model Drug From Liposomes
(IEEE, 2019)
This paper researches a suitable mathematical model that can reliably predict the release of a model drug (namely calcein) from biologically targeted liposomal nanocarriers triggered by ultrasound. Using mathematical models, ...
Use of Model Predictive Control and Artificial Neural Networks to Optimize the Ultrasonic Release of a Model Drug From Liposomes
(IEEE, 2017)
The use of echogenic liposomes to deliver chemotherapeutic agents for cancer treatment has gained wide recognition in the last 20 years. Cancerous cells can develop multiple drug resistance (MDR), in part, due to the drop ...
Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs)
(Bentham Science Publishers, 2017)
Cancer is the uncontrolled growth of cells in the body and is considered as one of the major causes of death globally. There are several cytotoxic chemotherapeutic agents used to treat cancer including methotrexate, ...
Doxorubicin-encapsulated Albumin liposomes with acoustic triggering for cancer treatment
(2019-05)
With cancer being the leading cause of death worldwide, increasing economic and social resources are being directed by researchers and healthcare professionals to treat the disease, or at least provide palliative care to ...
The Effect of Ultrasound on the Drug Delivery of RGD-Targeted Liposomes
(2018-05)
Approaches used to treat cancer, with the most prominent being chemotherapy, have detrimental effects on patients’ health. Doxorubicin, a chemotherapeutic agent, alters normal cellular functions and can cause many fatal ...