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    Ultrasound Triggered Release of Estrone- Targeted Liposomes 

    Kawak, Pierre (2017-05)
    The fight against cancer has proven to be a lengthy one. Conventional treatment of cancer usually involves chemotherapy, a therapy known for its detrimental side effects. Doxorubicin, a cytotoxic anthracycline antibiotic, ...
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    Doxorubicin-encapsulated Albumin liposomes with acoustic triggering for cancer treatment 

    Farooq, Afifa (2019-05)
    With cancer being the leading cause of death worldwide, increasing economic and social resources are being directed by researchers and healthcare professionals to treat the disease, or at least provide palliative care to ...
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    Release of Doxorubicin from Unstabilized and Stabilized Micelles Under the Action of Ultrasound 

    Husseini, Ghaleb; Diaz de la Rosa, Mario A.; Gabuji, Tasneem; Zeng, Yi; Christensen, Douglas A.; Pitt, William G. (American Scientific Publishers, 2007)
    Polymeric micelles are being investigated as chemotherapy drug delivery carriers using ultrasound as a trigger mechanism. The aim of this paper is to measure the release of Doxorubicin (Dox) from the core of unstabilized ...
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    Preliminary Results of Combining Low Frequency Low Intensity Ultrasound and Liposomal Drug Delivery to Treat Tumors in Rats 

    Pitt, William G.; Husseini, Ghaleb; Roeder, Beverly L.; Dickinson, David J.; Warden, David R.; Hartley, Jonathan M.; Jones, Peter W. (American Scientific Publishers, 2011)
    Ultrasound is a convenient trigger for site-specific drug delivery in cancer therapy. Nanosized liposomes formulated from soy phosphatidyl choline, cholesterol, 1,2-distearoyl-sn-glycero- 3-phosphoethanolamine-N-[carboxy ...
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    Facile Ultrasound-Triggered Release of Calcein and Doxorubicin from Iron-Based Metal-Organic Frameworks 

    Ibrahim, Mihad; Sabouni, Rana; Husseini, Ghaleb; Karami, Abdollah; Bai, Reenu Geetha; Mukhopadhyay, Debasmita (American Scientific Publishers, 2020)
    Metal-organic frameworks (MOFs) are promising new nanocarriers with potential use in anticancer drug delivery. However, there is a scarcity of studies on the uptake and release of guest molecules associated with MOF ...
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    DNA damage induced by micellar-delivered doxorubicin and ultrasound: comet assay study 

    Husseini, Ghaleb; El-Fayoumi, Refaat I.; O'Neill, Kim L.; Rapoport, Natalya Y.; Pitt, William G. (Elsevier, 2000)
    To minimize adverse side effects of chemotherapy, we have developed a micellar drug carrier that retains hydrophobic drugs, and then releases the drug by ultrasonic stimulation. This study investigated the DNA damage induced ...
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    Factors affecting acoustically triggered release of drugs from polymeric micelles 

    Husseini, Ghaleb; Myrup, Gregg D.; Pitt, William G.; Christensen, Douglas A.; Rapoport, Natalya Y. (Elsevier, 2000)
    A custom ultrasonic exposure chamber with real-time fluorescence detection was used to measure acoustically-triggered drug release from Pluronic P-105 micelles under continuous wave (CW) or pulsed ultrasound in the frequency ...
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    Ultrasonic release of doxorubicin from Pluronic P105 micelles stabilized with an interpenetrating network of N,N diethylacrylamide 

    Husseini, Ghaleb; Christensen, Douglas A.; Rapoport, Natalya Y.; Pitt, William G. (Elsevier, 2002)
    Pluronic P105 micelles sequester hydrophobic drugs and release them upon insonation with low frequency ultrasound; however these micelles dissolve relatively quickly upon dilution. The objective of this research was to ...
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    The Comet Assay to Determine the Mode of Cell Death for the Ultrasonic Delivery of Doxorubicin to Human Leukemia (HL-60 Cells) from Pluronic P105 Micelles 

    Husseini, Ghaleb; O'Neill, Kim L.; Pitt, William G. (Adenine Press, 2005)
    This notes examines the mode of cell death of HL-60 cells exposed to 70 kHz and 1.3 W/cm2 ultrasound in the presence of 1% Pluronic P105 and 1.67 μg/ml doxorubicin (Dox). The cells were ultrasonicated for 30, 60, and 120 ...
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    Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery 

    Staples, Bryant J.; Pitt, William G.; Roeder, Beverly L.; Husseini, Ghaleb; Rajeev, Deepthi; Schaalje, G. Bruce (Elsevier, 2010)
    Ultrasound (US) increases efficacy of drugs delivered from micelles, but the pharmacokinetics have not been studied previously. In this study, US was used to deliver doxorubicin (Dox) sequestered in micelles in an in vivo ...
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    AuthorPitt, William G. (8)Husseini, Ghaleb (5)Husseini Ghaleb (4)Christensen, Douglas A. (3)Rapoport, Natalya Y. (3)O'Neill, Kim L. (2)Roeder, Beverly L. (2)Bai, Reenu Geetha (1)Diaz de la Rosa, Mario A. (1)Dickinson, David J. (1)... View MoreSubject
    Doxorubicin (11)
    Ultrasound (11)
    Drug Delivery (3)Drug delivery (3)Liposomes (3)Micellar drug delivery (3)Cancer (2)Pluronic (2)Ultrasonics in medicine (2)Active Targeting (1)... View MoreDate Issued2010 - 2020 (5)2000 - 2009 (6)Has File(s)Yes (11)

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