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The Use of Transferrin and Ultrasound in Cancer Treatment
(2019-05)
Site-specific drug delivery represents an attractive approach in cancer treatment to reduce the undesirable side-effects of anticancer therapeutics and increase the accumulation of drugs at tumor sites. Surface modification ...
Doxorubicin-encapsulated Albumin liposomes with acoustic triggering for cancer treatment
(2019-05)
With cancer being the leading cause of death worldwide, increasing economic and social resources are being directed by researchers and healthcare professionals to treat the disease, or at least provide palliative care to ...
Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer
(2018-12)
Cancer is one of the deadliest diseases in this era. Since conventional treatment has many side effects, its use is limited, which augments the need for new smart drug delivery systems, such as nanocarriers, capable of ...
A Novel Cancer Treatment Platform Utilizing HER2-Immunoliposomes and Ultrasound
(2020-05)
Cancer is defined as the uncontrolled growth of cells in the body. It is one of the leading causes of death worldwide. One of the most common approaches to destroy cancer cells is via chemotherapy treatment, in which ...
Factors affecting acoustically triggered release of drugs from polymeric micelles
(Elsevier, 2000)
A custom ultrasonic exposure chamber with real-time fluorescence detection was used to measure acoustically-triggered drug release from Pluronic P-105 micelles under continuous wave (CW) or pulsed ultrasound in the frequency ...
Ultrasonic-Activated Micellar Drug Delivery for Cancer Treatment
(Wiley InterSciences, 2008)
The use of nanoparticles and ultrasound in medicine continues to evolve. Great strides have been made in the areas of producing micelles, nanoemulsions, and solid nanoparticles that can be used in drug delivery. An effective ...
Role of frequency and mechanical index in ultrasonic-enhanced chemotherapy in rats
(Springer, 2009)
Purpose The therapeutic effect of ultrasound and micellar-encapsulated doxorubicin was studied in vivo using a tumor-bearing rat model with emphasis on how tumor growth rate is affected by ultrasonic parameters such as ...
Micelles and nanoparticles for ultrasonic drug and gene delivery
(Elsevier, 2008)
Drug delivery research employing micelles and nanoparticles has expanded in recent years. Of particular interest is the use of these nanovehicles that deliver high concentrations of cytotoxic drugs to diseased tissues ...
Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery
(Elsevier, 2010)
Ultrasound (US) increases efficacy of drugs delivered from micelles, but the pharmacokinetics have not been studied previously. In this study, US was used to deliver doxorubicin (Dox) sequestered in micelles in an in vivo ...