Search
Now showing items 1-10 of 82
The effect of pegylation and targeting moieties on the ultrasound-mediated drug release from liposomes
(ACS Publications, 2019)
The use of targeted liposomes encapsulating chemotherapy drugs enhances the specific targeting of cancer cells, thus, reducing the side effects of these agents and providing a more patient-friendly treatment. Targeted ...
Ultrasonically Controlled Albumin-conjugated Liposomes for Breast Cancer Therapy
(Taylor and Francis Online, 2019)
Targeted liposomes have high potentials in the specific and effective delivery of their loaded therapeutic agents to the tumor site. Once at the tumor site, it is important that these liposomes are triggered to release ...
Carbohydrate-Functionalized Liposomes In Cancer Therapy
(Bentham Science, 2020)
Existing cancer treatments are often accompanied by adverse side effects that can greatly reduce the quality of life of cancer patients; this sets the platform for the development and application of nanocarrier-based ...
Immunoliposomes: Synthesis, Structure, and Their Potential as Drug Delivery Carriers
(Bentham Science, 2020)
Immunoliposomes have emerged as attractive drug targeting vehicles for cancer treatment. This review presents the recent advances in the design of immunoliposomes encapsulating a variety of chemotherapeutic agents. We ...
Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review
(American Scientific Publishers, 2020)
The use of ultrasound as a medical diagnostic tool began in the 1940s. Ever since, the medical applications of ultrasound have included imaging, tumor ablation, and lithotripsy; however, an ever-increasing body of literature ...
Synergistic Nanomedicine: Passive, Active, and Ultrasound-Triggered Drug Delivery in Cancer Treatment
(American Scientific Publishers, 2015)
Nanocarriers are heavily researched as drug delivery vehicles capable of sequestering antineoplastic agents and then releasing their contents at the desired location. The feasibility of using such carriers stems from their ...
The Use of Ultrasound and Micelles in Cancer Treatment
(American Scientific Publishers, 2008)
The high toxicity of potent chemotherapeutic drugs like Doxorubicin (Dox) limits the therapeutic window in which they can be applied. This window can be expanded by controlling the drug delivery in both space and time such ...
Non-Viral Gene Transfection with Ultrasound: Is 100% Transfection Possible?
(American Scientific Publishers, 2012)
Ultrasound has been used as a modality to enhance the transfection of cells, purportedly via entry of genetic material through defects in the cell membrane produced by bubble cavitation events. A mathematical model was ...
Factors Affecting the Acoustic In Vitro Release of Calcein from PEGylated Liposomes
(American Scientific Publishers, 2019)
Typical methods used in cancer treatment, including chemotherapy, are debilitating because of the various adverse side effects experienced by cancer patients. The free drug injected into the patient at given doses affects ...
Measuring the Acoustic Release of a Chemotherapeutic Agent from Folate-Targeted Polymeric Micelles
(American Scientific Publishers, 2018)
In this paper, we compare the use of Bayesian filters for the estimation of release and reencapsulation rates of a chemotherapeutic agent (namely Doxorubicin) from nanocarriers in an acoustically activated drug release ...