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Use of Model Predictive Control and Artificial Neural Networks to Optimize the Ultrasonic Release of a Model Drug From Liposomes
The use of echogenic liposomes to deliver chemotherapeutic agents for cancer treatment has gained wide recognition in the last 20 years. Cancerous cells can develop multiple drug resistance (MDR), in part, due to the drop ...
Identification of the Uncertainty Structure to Estimate the Acoustic Release of Chemotherapeutics From Polymeric Micelles
This paper estimates the acoustic drug release from micelles after accurately identifying the underlying statistical noise characteristics in experimental data. The drug release is measured as a change in fluorescence as ...