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Immunomodulatory and Anti-Inflammatory Effects of Berberine in Lung Tissue and its Potential Application in Prophylaxis and Treatment of COVID-19
(IMR Press, 2022)
Natural products with known safety profiles are a promising source for the discovery of new drug leads. Berberine presents an example of one such phytochemical that has been extensively studied for its anti-inflammatory ...
Potential immunomodulatory role of sesamin in combating immune dysregulation associated with COVID-19
(Medknow Publications, 2021)
The ongoing outbreak of novel coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused an unprecedented global health crisis. Development of a cure for this ...
Anti-Bacterial and Anti-Fungal Activity of Xanthones Obtained via Semi-Synthetic Modification of α-Mangostin from Garcinia mangostana
(MDPI, 2017)
The microbial contamination in food packaging has been a major concern that has paved the way to search for novel, natural anti-microbial agents, such as modified α-mangostin. In the present study, twelve synthetic analogs ...
Analysis of macro and micro elemental composition of different extracts and finished products of the medicinal Herb – Terminalia bellirica
(PKP, 2019)
Terminalina bellirica is considered to be a sacred plant with five distinctive tastes (sweet, sour, salty, bitter, and pungent). It stimulates the proper functioning of the digestive system, sensory organs and it is very ...
Preparation and characterization of gatifloxacin-loaded sodium alginate hydrogel membranes supplemented with hydroxypropyl methylcellulose and hydroxypropyl cellulose polymers for wound dressing
(PKP, 2016)
Introduction: The aim of this study is to evaluate gatifloxacin-loaded sodium alginate hydrogel membranes, supplemented with glycerol (a plasticizer), glutaraldehyde (a cross-linking agent), and hydroxypropyl methylcellulose ...
Evaluation of the interaction potential of synthetic ethylene glycol compounds with nuclear Factor κB
(PKP, 2013)
In the last three decades, nuclear factor κB (NF-κB) has been the focus of many researchers who are interested in understanding the various molecular mechanisms involved in inflammatory diseases and cancer. Interference ...
Efficient and simple protocol employing borohydride systems to design a selective osthol-zirconium (OST-Zr) library from potential natural products
(PKP, 2016)
“Drug likeness” of a molecule is the prime criterion for a molecule to exhibit the desired pharmaceutical activity. A pharmacophore, which describes molecular features that are necessary for molecular recognition of a ...
Green Synthesis of Encapsulated Copper Nanoparticles Using a Hydroalcoholic Extract of Moringa oleifera Leaves and Assessment of Their Antioxidant and Antimicrobial Activities
(MDPI, 2020)
The synthesis of metal nanoparticles using plant extracts is a very promising method in green synthesis. The medicinal value of Moringa oleifera leaves and the antimicrobial activity of metallic copper were combined in the ...