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Release of Doxorubicin from Unstabilized and Stabilized Micelles Under the Action of Ultrasound
(American Scientific Publishers, 2007)
Polymeric micelles are being investigated as chemotherapy drug delivery carriers using ultrasound as a trigger mechanism. The aim of this paper is to measure the release of Doxorubicin (Dox) from the core of unstabilized ...
Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery
(Elsevier, 2010)
Ultrasound (US) increases efficacy of drugs delivered from micelles, but the pharmacokinetics have not been studied previously. In this study, US was used to deliver doxorubicin (Dox) sequestered in micelles in an in vivo ...
DNA damage induced by micellar-delivered doxorubicin and ultrasound: comet assay study
(Elsevier, 2000)
To minimize adverse side effects of chemotherapy, we have developed a micellar drug carrier that retains hydrophobic drugs, and then releases the drug by ultrasonic stimulation. This study investigated the DNA damage induced ...
Ultrasonic release of doxorubicin from Pluronic P105 micelles stabilized with an interpenetrating network of N,N diethylacrylamide
(Elsevier, 2002)
Pluronic P105 micelles sequester hydrophobic drugs and release them upon insonation with low frequency ultrasound; however these micelles dissolve relatively quickly upon dilution. The objective of this research was to ...
Preliminary Results of Combining Low Frequency Low Intensity Ultrasound and Liposomal Drug Delivery to Treat Tumors in Rats
(American Scientific Publishers, 2011)
Ultrasound is a convenient trigger for site-specific drug delivery in cancer therapy. Nanosized liposomes formulated from soy phosphatidyl choline, cholesterol, 1,2-distearoyl-sn-glycero- 3-phosphoethanolamine-N-[carboxy ...
Factors affecting acoustically triggered release of drugs from polymeric micelles
(Elsevier, 2000)
A custom ultrasonic exposure chamber with real-time fluorescence detection was used to measure acoustically-triggered drug release from Pluronic P-105 micelles under continuous wave (CW) or pulsed ultrasound in the frequency ...