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Functionalized Metal Organic Frameworks For Chemotherapy Drug Delivery
(2020-11)
Cancer is the leading cause of death worldwide, and can be treated by various methods or sometimes a combination of different treatments. Chemotherapy is one of the conventional methods of treatment. Although it is effective ...
In Vitro Cell Work of Two Types of Targeted Nanoparticles with Ultrasound Triggering
(2020-11)
Targeted liposomes have shown promising potential as effective chemotherapeutics delivery vehicles in Smart Drug Delivery Systems (SDDSs). Upon accumulation and internalization at the tumor site, the liposomes need to be ...
Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review
(American Scientific Publishers, 2020)
The use of ultrasound as a medical diagnostic tool began in the 1940s. Ever since, the medical applications of ultrasound have included imaging, tumor ablation, and lithotripsy; however, an ever-increasing body of literature ...
The Effects of cRGD Targeting Liposomes When Paired With Ultrasonic Waves on Drug Delivery
(2021-04)
Cancer is a leading fatal disease, which has the ability to grow uncontrollably and spread throughout the body of the patient. Several approaches have been used to treat cancer, chemotherapy being the most common treatment ...
Ultrasound-sensitive cRGD-modified liposomes as a novel drug delivery system
(Taylor & Francis, 2022)
Targeted liposomes enable the delivery of encapsulated chemotherapeutics to tumours by targeting specific receptors overexpressed on the surfaces of cancer cells; this helps in reducing the systemic side effects associated ...
Hybrid Liposome/Metal–Organic Framework as a Promising Dual-Responsive Nanocarriers for Anticancer Drug Delivery
(Elsevier, 2022)
In this work, liposome-coated iron (III) benzene-1,3,5-tricarboxylate (Fe-BTC) metal–organic framework is examined as a promising pH/Ultrasound dual-responsive nanocarriers for doxorubicin (DOX) delivery. The successful ...
Modeling of In vitro Release Kinetics of Ultrasound-triggered Targeted Liposomes
(2022-04)
Ultrasound-triggered, targeted liposomes are a promising drug delivery system as they potentially improve the clinical outcomes of chemotherapy while reducing associated side effects. However, the common drug release models ...
Ultrasound Triggering of Liposomal Nanodrugs for Cancer Therapy: A Review
(MDPI, 2022)
Efficient conventional chemotherapy is limited by its nonspecific nature, which causes severe systemic toxicity that can lead to patient discomfort and low therapeutic efficacy. The emergence of smart drug delivery systems ...
Combined and Single Doxorubicin/Naproxen Drug Loading and Dual-Responsive pH/Ultrasound Release from Flexible Metal-Organic Framework Nanocarriers
(American Scientific Publishers, 2022)
In this study, the flexible aluminum-based MIL-53(Al) metal-organic framework was loaded with doxorubicin (DOX) and naproxen (NAP) and was examined as a promising pH/ultrasound dual-responsive drug delivery system. The two ...
The Kinetics of Calcein Release from Mixed Targeted Liposomes Using Ultrasound
(American Scientific Publishers, 2022)
Site-specific delivery of chemotherapeutics using actively targeted-stimuli-responsive liposomes is a promising approach to enhance the therapeutic efficiency of anti-cancer drugs while reducing the associated undesirable ...