Show simple item record

dc.contributor.authorHusseini, Ghaleb
dc.contributor.authorO'Neill, Kim L.
dc.contributor.authorPitt, William G.
dc.date.accessioned2021-01-14T06:59:24Z
dc.date.available2021-01-14T06:59:24Z
dc.date.issued2005
dc.identifier.citationGhaleb A. Husseini, Kim L. O'Neill, William G. Pitt, The Comet Assay to Determine the Mode of Cell Death for the Ultrasonic Delivery of Doxorubicin to Human Leukemia (HL-60 Cells) from Pluronic P105 Micelles, Technology in Cancer Research & Treatment, vol. 4, 6: pp. 707-711.en_US
dc.identifier.issn1533-0346
dc.identifier.urihttp://hdl.handle.net/11073/21271
dc.description.abstractThis notes examines the mode of cell death of HL-60 cells exposed to 70 kHz and 1.3 W/cm2 ultrasound in the presence of 1% Pluronic P105 and 1.67 μg/ml doxorubicin (Dox). The cells were ultrasonicated for 30, 60, and 120 minutes. They were then lysed, electrophorised, stained using propidium iodide, and their DNA profile captured using a fluorescent microscope. The gradual DNA damage observed and the comet tails captured after one and two hours of insonation suggest that the mode of cell killing is apoptosis.en_US
dc.description.sponsorshipCollege of Engineeringen_US
dc.description.sponsorshipDepartment of Chemical Engineeringen_US
dc.language.isoen_USen_US
dc.publisherAdenine Pressen_US
dc.relation.ispartofseriesAmerican University of Sharjah Faculty Worken_US
dc.relation.urihttps://doi.org/10.1177/153303460500400616en_US
dc.subjectMicellar drug deliveryen_US
dc.subjectDoxorubicinen_US
dc.subjectComet Assayen_US
dc.subjectUltrasounden_US
dc.subjectApoptosisen_US
dc.titleThe Comet Assay to Determine the Mode of Cell Death for the Ultrasonic Delivery of Doxorubicin to Human Leukemia (HL-60 Cells) from Pluronic P105 Micellesen_US
dc.typePeer-Revieweden_US
dc.typeArticleen_US
dc.typePostprinten_US
dc.identifier.doi10.1177/153303460500400616


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record