Department of Biology, Chemistry and Environmental Sciences
Work by the faculty and students of the Department of Biology, Chemistry and Environmental Sciences
Recent Submissions
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Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres
(Royal Society, 2024-04-17)This study focuses on the development of antimicrobial fibres for use in medical and healthcare textile industries. Carbon dots (CDs) were designed with boronic acid groups for the attachment to cellulose fibres found in ... -
Environmental Management Systems in Public Sector
(Edward Elgar, 2023)This chapter focuses on environmental management systems (EMS) in public sector organisations (PSOs). Our objectives are to 1) explain what is an EMS, describe the two main EMS standards (ISO 14001 and EMAS) and how to ... -
Enhancement of the corrosion resistance of mild steel with femtosecond laser- nanostructuring and CrCoNi medium entropy alloy coating
(Elsevier, 2022)In this work, the corrosion resistance of mild steel surface nanostructured with a femtosecond laser and coated with high corrosion resistant CrCoNi (CCN) medium entropy alloy through magnetron sputtering is studied. ... -
Drivers, Challenges and Outcomes of Environmental Management System Implementation in Public Sector Organizations: A Systematic Review of Empirical Evidence
(MDPI, 2023-04-28)Our research objectives were to conduct a systematic literature review of the empirical articles on the drivers, challenges and outcomes of environmental management system (EMS) implementation in public sector organizations ... -
Insights into rechargeable Zn-air batteries for future advancements in energy storing technology
(Elsevier, 2023-02-27)Owing to its high theoretical specific energy density, low cost, abundance and environmental friendliness, the rechargeable Zn-Air batteries (ZAB) are becoming the most prevalent candidate as energy storage devices for ... -
The Role of AEBP1 in Sex-Specific Diet-Induced Obesity
(Springer Nature, 2005)Obesity is an important risk factor for heart disease, diabetes, and certain cancers, but the molecular basis for obesity is poorly understood. The transcriptional repressor AEBP₁, which functions as a negative regulator ... -
Adipocyte Enhancer-binding Protein-1 Promotes Macrophage Inflammatory Responsiveness by Up-Regulating NF-κB via IκBα Negative Regulation
(The American Society for Cell Biology, 2007)Nuclear factor κB (NF-κB) subunits comprise a family of eukaryotic transcription factors that are critically involved in cell proliferation, inflammation, and apoptosis. Under basal conditions, NF-κB subunits are kept under ... -
The trans-10, cis-12 isomer of conjugated linoleic acid decreases adiponectin assembly by PPARγ-dependent and PPARγ-independent mechanisms
(Elsevier, 2008)The adipocyte-derived secretory protein adiponectin functions as an insulin-sensitizing agent. In plasma, adiponectin exists as low, medium, and high molecular weight oligomers. Treatment with trans-10, cis-12 conjugated ... -
PPARγ1 and LXRα face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP1
(Sage, 2010)Peroxisome proliferator-activated receptor γ1 (PPARγ1) and liver X receptor α (LXRα) are nuclear receptors that play pivotal roles in macrophage cholesterol homeostasis and inflammation; key biological processes in ... -
Regulation of I𝜅B𝛼 Function and NF-𝜅B Signaling: AEBP1 Is a Novel Proinflammatory Mediator in Macrophages
(Hindawi, 2010)NF-𝜅B comprises a family of transcription factors that are critically involved in various inflammatory processes. In this paper, the role of NF-𝜅B in inflammation and atherosclerosis and the regulation of the NF-𝜅B ... -
Lactation Defect with Impaired Secretory Activation in AEBP1-Null Mice
(Public Library of Science, 2011)Adipocyte enhancer binding protein 1 (AEBP1) is a multifunctional protein that negatively regulates the tumor suppressor PTEN and IκBα, the inhibitor of NF-κB, through protein-protein interaction, thereby promoting cell ... -
Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mice
(Springer Nature, 2011)Atherogenesis is a long-term process that involves inflammatory response coupled with metabolic dysfunction. Foam cell formation and macrophage inflammatory response are two key events in atherogenesis. Adipocyte ... -
A Density Functional Theory Study of the Cu⁺ · O₂ and Cu⁺ · N₂ Adducts
(De Gruyter, 2011)The geometries and harmonic vibration frequencies of the Cu⁺·O₂ and Cu⁺ ·N₂ are determined by various density functional theory (DFT) methods employing different basis sets. The potential energy surfaces (PES) are examined. ... -
Stromal Adipocyte Enhancer-binding Protein (AEBP1) Promotes Mammary Epithelial Cell Hyperplasia via Proinflammatory and Hedgehog Signaling
(Elsevier, 2012)Disruption of mammary stromal-epithelial communication leads to aberrant mammary gland development and induces mammary tumorigenesis. Macrophages have been implicated in carcinogenesis primarily by creating an inflammatory ... -
Evaluation of the interaction potential of synthetic ethylene glycol compounds with nuclear Factor κB
(PKP, 2013)In the last three decades, nuclear factor κB (NF-κB) has been the focus of many researchers who are interested in understanding the various molecular mechanisms involved in inflammatory diseases and cancer. Interference ... -
Recent advances on the anti-cancer properties of Nigella sativa, a widely used food additive
(Elsevier, 2016)The use of naturally-occurring agents to regulate tumorigenesis is on the rise. Several herbal extracts, pure plant-derived active constituents, and food additives have been reported to possess potent anti-cancer properties ... -
Anti-Bacterial and Anti-Fungal Activity of Xanthones Obtained via Semi-Synthetic Modification of α-Mangostin from Garcinia mangostana
(MDPI, 2017)The microbial contamination in food packaging has been a major concern that has paved the way to search for novel, natural anti-microbial agents, such as modified α-mangostin. In the present study, twelve synthetic analogs ... -
Analysis of macro and micro elemental composition of different extracts and finished products of the medicinal Herb – Terminalia bellirica
(PKP, 2019)Terminalina bellirica is considered to be a sacred plant with five distinctive tastes (sweet, sour, salty, bitter, and pungent). It stimulates the proper functioning of the digestive system, sensory organs and it is very ... -
AEBP1 is a Novel Oncogene: Mechanisms of Action and Signaling Pathways
(Hindawi, 2020)Adipocyte enhancer-binding protein 1 (AEBP1) is a transcriptional repressor involved in the regulation of critical biological processes including adipogenesis, mammary gland development, inflammation, macrophage cholesterol ... -
Organ-specific toxicity evaluation of stearamidopropyl dimethylamine (SAPDMA) surfactant using zebrafish embryos
(Elsevier, 2020)Surfactants are widely used in the industry of detergents, household products, and cosmetics. SAPDMA is a cationic surfactant that is used mostly in cosmetics, conditioning agents and has recently gained attention as a ...
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