Now showing items 1-3 of 3

    • Gold-Conjugated Curcumin as a Novel Therapeutic Agent against Brain-Eating Amoebae 

      Mungroo, Mohammad Ridwane; Anwar, Ayaz; Khan, Naveed; Siddiqui, Ruqaiyyah (ACS Publications, 2020)
      Balamuthia mandrillaris and Naegleria fowleri are free-living amoebae that cause infection of the central nervous system, granulomatous amoebic encephalitis (GAE) and primary amoebic meningoencephalitis (PAM), respectively. ...
    • Novel Azoles as Antiparasitic Remedies against Brain-Eating Amoebae 

      Anwar, Ayaz; Mungroo, Mohammad Ridwane; Khan, Simal; Fatima, Itrat; Rafique, Rafaila; Khan, Khalid Mohammed; Siddiqui, Ruqaiyyah; Khan, Naveed (MDPI, 2020)
      Balamuthia mandrillaris and Naegleria fowleri are opportunistic protozoan pathogens capable of producing infection of the central nervous system with more than 95% mortality rate. Previously, we have synthesized several ...
    • Novel insights into the potential role of ion transport in sensory perception in Acanthamoeba 

      Siddiqui, Ruqaiyyah; Roberts, Stephen K.; Ong, Timothy Yu Yee; Mungroo, Mohammad Ridwane; Anwar, Areeba; Khan, Naveed Ahmed (Springer Nature, 2019)
      Background: Acanthamoeba is well known to produce a blinding keratitis and serious brain infection known as encephalitis. Effective treatment is problematic, and can continue up to a year, and even then, recurrence can ...