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Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment
(2016-01)
Chemotherapy is frequently used in cancer treatment. However, side effects associated with this type of treatment are often detrimental to the patient's health. This thesis discusses a novel approach of delivering a cytotoxic ...
The Use of Transferrin and Ultrasound in Cancer Treatment
(2019-05)
Site-specific drug delivery represents an attractive approach in cancer treatment to reduce the undesirable side-effects of anticancer therapeutics and increase the accumulation of drugs at tumor sites. Surface modification ...
Using a Cavitation Model to Represent the Acoustic Release Kinetics from Folated Micelles
(2014-12)
Anti-neoplastic drugs used for cancer treatment have various damaging effects on healthy cells, leading to several side effects in patients undergoing chemotherapy. The encapsulation of these agents in nanoparticles, such ...
Ultrasound Triggered Release of Estrone- Targeted Liposomes
(2017-05)
The fight against cancer has proven to be a lengthy one. Conventional treatment of cancer usually involves chemotherapy, a therapy known for its detrimental side effects. Doxorubicin, a cytotoxic anthracycline antibiotic, ...
Doxorubicin-encapsulated Albumin liposomes with acoustic triggering for cancer treatment
(2019-05)
With cancer being the leading cause of death worldwide, increasing economic and social resources are being directed by researchers and healthcare professionals to treat the disease, or at least provide palliative care to ...
The Effect of Ultrasound on the Drug Delivery of RGD-Targeted Liposomes
(2018-05)
Approaches used to treat cancer, with the most prominent being chemotherapy, have detrimental effects on patients’ health. Doxorubicin, a chemotherapeutic agent, alters normal cellular functions and can cause many fatal ...
Liposomal drug release using ultrasound and modeling release dynamics for model predictive controller design
(2015-06)
Chemotherapy is widely used for cancer treatment; however, it causes unwanted side effects in patients such as fatigue, weight loss, pain, hair fall and nausea. Those side effects are due to the fact that most of the ...
Lipsome-coated metal organic frameworks as a new drug nanocarrier
(2019-12)
Cancer has emerged to become one of the predominant diseases ever known to humanity, with chemotherapeutic agents as leading methods for treating it. However, this blind-sighted treatment method that targets all cells; ...
Preparation of albumin-targeted liposomes and the study of their release characteristics using ultrasound
(2016-01)
The main objective of this thesis was to investigate the enhancement of drug delivery using targeted liposomes triggered by ultrasound. In this thesis, a thorough literature review on cancer and drug delivery systems ...
Investigating and Modeling the Acoustic Release of Doxorubicin from Folate Targeted Micelles
(2012-06)
To minimize the adverse side effects of conventional chemotherapy, a targeted micellar drug carrier was investigated that retains hydrophobic drugs in its core and then releases the drug via ultrasound. This thesis reports ...