Browsing Department of Chemical and Biological Engineering by Title
Now showing items 167-186 of 187
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Ultrasonic Drug Delivery Using Micelles and Liposomes
(Springer, 2016)The encapsulation of drugs in nanocarriers revolutionized research in drug delivery, especially in cancer chemotherapeutics. Several nanosystems have been developed including liposomes, polymeric micelles, dendrimers, solid ... -
Ultrasonic release of doxorubicin from Pluronic P105 micelles stabilized with an interpenetrating network of N,N diethylacrylamide
(Elsevier, 2002)Pluronic P105 micelles sequester hydrophobic drugs and release them upon insonation with low frequency ultrasound; however these micelles dissolve relatively quickly upon dilution. The objective of this research was to ... -
Ultrasonic-Activated Micellar Drug Delivery for Cancer Treatment
(Wiley InterSciences, 2008)The use of nanoparticles and ultrasound in medicine continues to evolve. Great strides have been made in the areas of producing micelles, nanoemulsions, and solid nanoparticles that can be used in drug delivery. An effective ... -
Ultrasonically Controlled Albumin-conjugated Liposomes for Breast Cancer Therapy
(Taylor and Francis Online, 2019)Targeted liposomes have high potentials in the specific and effective delivery of their loaded therapeutic agents to the tumor site. Once at the tumor site, it is important that these liposomes are triggered to release ... -
Ultrasonically triggered drug delivery: Breaking the barrier
(Elsevier, 2014)The adverse side-effects of chemotherapy can be minimized by delivering the therapeutics in time and space to only the desired target site. Ultrasound offers one fairly non-invasive method of accomplishing such precise ... -
Ultrasound in drug and gene delivery
(Elsevier, 2008)In this issue, we present the current applications and future prospects of ultrasound in various aspects of drug and gene delivery. There are many advantages to ultrasound that make it ideal for the delivery of therapeutics ... -
Ultrasound Triggering of Liposomal Nanodrugs for Cancer Therapy: A Review
(MDPI, 2022)Efficient conventional chemotherapy is limited by its nonspecific nature, which causes severe systemic toxicity that can lead to patient discomfort and low therapeutic efficacy. The emergence of smart drug delivery systems ... -
Ultrasound-Induced Calcein Release From eLiposomes
(Elsevier, 2012)Ultrasound is explored as a method of inducing the release of encapsulated materials from eLiposomes, defined as liposomes containing emulsion droplets. Emulsions were formed using perfluorohexane and perfluoropentane. ... -
Ultrasound-induced doxorubicin release from folate-targeted and non-targeted P105 micelles: a modeling study
(De Gruyter, 2016)The aim of this work is to study the kinetics of ultrasound (70 kHz) – using a kinetic model that takes into account cavitation events and drug re-encapsulation upon the cessation of the acoustic field. The simulation ... -
Ultrasound-Mediated Cancer Therapeutics Delivery using Micelles and Liposomes: A Review
(Bentham Science Publisher, 2021)Nanoparticles have proven promising as cancer theranostic tools. Nanoparticles are selective in nature, have reduced toxicity, and controllable drug release patterns making them ideal carriers for anticancer drugs. Numerous ... -
Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review
(American Scientific Publishers, 2020)The use of ultrasound as a medical diagnostic tool began in the 1940s. Ever since, the medical applications of ultrasound have included imaging, tumor ablation, and lithotripsy; however, an ever-increasing body of literature ... -
Ultrasound-responsive Nanocarriers in Cancer Treatment: a review
(American Chemical Society, 2021)The safe and effective delivery of anticancer agents to diseased tissues is one of the significant challenges in cancer therapy. Conventional anticancer agents are generally cytotoxins with poor pharmacokinetics and ... -
Ultrasound-sensitive cRGD-modified liposomes as a novel drug delivery system
(Taylor & Francis, 2022)Targeted liposomes enable the delivery of encapsulated chemotherapeutics to tumours by targeting specific receptors overexpressed on the surfaces of cancer cells; this helps in reducing the systemic side effects associated ... -
Ultrasound-triggered Immunotherapy for Cancer Treatment: An Update
(Bentham, 2021) -
Ultrasound-Triggered Liposomes Encapsulating Quantum Dots as Safe Fluorescent Markers for Colorectal Cancer
(MDPI, 2021)Quantum dots (QDs) are a promising tool to detect and monitor tumors. However, their small size allows them to accumulate in large quantities inside the healthy cells (in addition to the tumor cells), which increases their ... -
Ultrasound-triggered Release from Micelles
(Royal Society of Chemistry, 2013) -
Ultrasound‑triggered herceptin liposomes for breast cancer therapy
(Nature, 2021)The functionalization of liposomes with monoclonal antibodies is a potential strategy to increase the specificity of liposomes and reduce the side-effects associated with chemotherapeutic agents. The active targeting of ... -
Use of Model Predictive Control and Artificial Neural Networks to Optimize the Ultrasonic Release of a Model Drug From Liposomes
(IEEE, 2017)The use of echogenic liposomes to deliver chemotherapeutic agents for cancer treatment has gained wide recognition in the last 20 years. Cancerous cells can develop multiple drug resistance (MDR), in part, due to the drop ... -
The Use of Ultrasound and Micelles in Cancer Treatment
(American Scientific Publishers, 2008)The high toxicity of potent chemotherapeutic drugs like Doxorubicin (Dox) limits the therapeutic window in which they can be applied. This window can be expanded by controlling the drug delivery in both space and time such ... -
The use of ultrasound to release chemotherapeutic drugs from micelles and liposomes
(Taylor & Francis, 2014)Several drug delivery systems have been investigated to reduce the side effects of chemotherapy by encapsulating the therapeutic agent in a nanosized carrier until it reaches the tumor site. Many of these particles are ...
