Now showing items 94-113 of 182

    • Mathematical modeling of microbubble cavitation at 70 kHz and the importance of the subharmonic in drug delivery from micelles 

      Diaz de la Rosa, Mario A.; Husseini, Ghaleb; Pitt, William G. (Elsevier, 2013)
      In order to gain insight into the experimental observation of ultrasound-induced release of drugs from micelles, we modeled the dynamic oscillations of a 10-μm-diameter bubble insonated at 70 kHz. The Parlitz modification ...
    • Measuring the Acoustic Release of a Chemotherapeutic Agent from Folate-Targeted Polymeric Micelles 

      Abusara, Ayah Mahmoud; Abdel-Hafez, Mamoun; Husseini, Ghaleb (American Scientific Publishers, 2018)
      In this paper, we compare the use of Bayesian filters for the estimation of release and reencapsulation rates of a chemotherapeutic agent (namely Doxorubicin) from nanocarriers in an acoustically activated drug release ...
    • Membrane bioreactor for wastewater treatment: A review 

      Al-Asheh, Sameer; Bagheri, Marzieh; Aidan, Ahmed (Elsevier, 2021)
      Due to the growth in the human population globally, it is noted that various industries have also grown. The need for an excess supply of water and the generation of high effluent quality upon proper treatment technologies ...
    • Micelles and nanoparticles for ultrasonic drug and gene delivery 

      Husseini, Ghaleb; Pitt, William G. (Elsevier, 2008)
      Drug delivery research employing micelles and nanoparticles has expanded in recent years. Of particular interest is the use of these nanovehicles that deliver high concentrations of cytotoxic drugs to diseased tissues ...
    • Microbial Desalination Cell (MDC) in the Presence of Activated Carbon 

      Aidan, Ahmed; Husseini, Ghaleb; Yemendzhiev, H.; Nenov, Valentin; Rasheed, Ami; Chekkath, Hiba (American Scientific Publishers, 2014-10)
      This report studies the performance of a Microbial Desalination Cell (MDC) in the presence ofactivated carbon in both the cathode and anode chambers. The large surface area of the activatedcarbon provides surface for ...
    • Microbial Desalination Cells Technology: A Review and a Case Study 

      Saeed, Henna M; Husseini, Ghaleb; Yousef, Sharifeh; Saif, Jawaria; Al-Asheh, Sameer; Azzam, Sara; Khawaga, Rehab Ibrahim; Abu Fara, Abdullah; Aidan, Ahmad (Elsevier, 2015-03)
      The microbial desalination cell (MDC) is a newly-developed technology which integrates the microbial fuel cell (MFC) process and electrodialysis for wastewater treatment, water desalination and production of renewable ...
    • Modeling and Bias-Robust Estimation of the Acoustic Release of Chemotherapeutics from Liposomes 

      Wadi, Ali; Abdel-Hafez, Mamoun; Husseini, Ghaleb (American Scientific Publishers, 2019)
      This paper models the acoustic drug release of chemotherapeutics from liposomes using a kinetic model that accounts for systematic biases affecting the drug delivery process. An optimal stochastic filter is then proposed ...
    • Modeling and Sensitivity Analysis of Acoustic Release of Doxorubicin from Unstabilized Pluronic P105 Using an Artificial Neural Network Model 

      Husseini, Ghaleb; Abdel-Jabbar, Nabil; Mjalli, Farouq Sabri; Pitt, William G. (Adenine Press, 2007)
      This paper models steady state acoustic release of Doxorubicin (Dox) from Pluronic P105 micelles using Artificial Neural Networks (ANN). Previously collected release data were compiled and used to train, validate, and test ...
    • Modeling of Anti-cancer Drug Release Kinetics from Liposomes and Micelles: A review 

      AlSawaftah, Nour Majdi; Paul, Vinod; Awad, Nahid S.; Husseini, Ghaleb (Institute of Electrical and Electronics Engineers, 2021)
      Nanocarriers, such as liposomes and micelles, were developed to enhance the delivery of therapeutic drugs to malignant tissues. Internal or external stimuli can be applied to achieve spatiotemporal controlled release from ...
    • Modeling of Drug Release Kinetics from Stimuli- Responsive Micelles and Liposomes: A review 

      AlSawaftah, Nour Majdi; Paul, Vinod; Awad, Nahid S.; Husseini, Ghaleb (IEEE, 2021)
      Nanocarriers such as micelles and liposomes were developed to enhance the delivery of therapeutic drugs to tumors. Internal or external stimuli can be applied to achieve spatiotemporal controlled release from these carriers. ...
    • Modeling of the In Vitro Release Kinetics of Sonosensitive Targeted Liposomes 

      Almajed, Zeyad Mohamed; Salkho, Najla; Sulieman, Hana; Husseini, Ghaleb (MDPI, 2022-12-05)
      Targeted liposomes triggered by ultrasound are a promising drug delivery system as they potentially improve the clinical outcomes of chemotherapy while reducing associated side effects. In this work, a comprehensive model ...
    • Modeling the Effects of Chemotherapy and Immunotherapy on Tumor Growth 

      El Haout, Sara; Fatani, Maymunah; Abu Farha, Nadia Khalil Mohammad; AlSawaftah, Nour Majdi; Mortula, Maruf; Husseini, Ghaleb (American Scientific Publishers, 2021)
      Mathematical modeling has been used to simulate the interaction of chemotherapy and immunotherapy drugs intervention with the dynamics of tumor cells growth. This work studies the interaction of cells in the immune system, ...
    • Multi-Model Investigation and Adaptive Estimation of the Acoustic Release of a Model Drug From Liposomes 

      Wadi, Ali; Abdel-Hafez, Mamoun; Husseini, Ghaleb; Paul, Vinod (IEEE, 2019)
      This paper researches a suitable mathematical model that can reliably predict the release of a model drug (namely calcein) from biologically targeted liposomal nanocarriers triggered by ultrasound. Using mathematical models, ...
    • Multifunctional Nanovehicles for Combined 5-Fluorouracil and Gold Nanoparticles Based on the Nanoprecipitation Method 

      Karmi, Abeer; Husseini, Ghaleb; Faroun, Maryam; Sowwan, Mukhles (American Scientific Publishers, 2011)
      To facilitate the administration of combined 5-Fluorouracil (5-FU) and gold nanoparticles (for photothermal treatment purposes), we developed 5-FU-gold-poly(lactide-co-glycolic acid) (5-FU-Au- PLGA) nanovehicles, via the ...
    • Nanoparticle-based materials in anticancer drug delivery: Current and future prospects 

      Ajith, Saniha Aysha; Almomani, Fares; Elhissi, Abdelbary; Husseini, Ghaleb (Elsevier, 2023)
      The past decade has witnessed a breakthrough in novel strategies to treat cancer. One of the most common cancer treatment modalities is chemotherapy which involves administering anti-cancer drugs to the body. However, these ...
    • Non-Viral Gene Transfection with Ultrasound: Is 100% Transfection Possible? 

      Pitt, William G.; Jack, Daniel R.; Husseini, Ghaleb; Memmott, Brett V. (American Scientific Publishers, 2012)
      Ultrasound has been used as a modality to enhance the transfection of cells, purportedly via entry of genetic material through defects in the cell membrane produced by bubble cavitation events. A mathematical model was ...
    • Novel algorithms for accurate DNA base-calling 

      Mohammed, Omniyah Gul; Assaleh, Khaled; Husseini, Ghaleb; Majdalawieh, Amin (Scientific Research Publishing, 2013)
      The ability to decipher the genetic code of different species would lead to significant future scientific achievements in important areas, including medicine and agriculture. The importance of DNA sequencing necessitated ...
    • Optimizing the use of ultrasound to deliver chemotherapeutic agents to cancer cells from polymeric micelles 

      Husseini, Ghaleb; Abdel-Jabbar, Nabil; Mjalli, Farouq Sabri; Pitt, William G.; Al-Mousa, Alaa Marwan Subhi (Elsevier, 2011)
      In this study, we present an artificial neural network (ANN) model that attempts to predict the dynamic release of doxorubicin (Dox) from P105 micelles under different ultrasonic power densities at 20 kHz. The goal is to ...
    • Optimum ethane recovery in conventional turboexpander process 

      Chebbi, Rachid; Al-Amoodi, Nahla S.; Abdel-Jabbar, Nabil; Husseini, Ghaleb; Al Mazroui, Khamis A. (Elsevier, 2010)
      Ethane recovery in a conventional turboexpander process is optimized considering different demethanizer pressures and different feeds: a lean gas and a rich one. The design variables are varied, while meeting process ...
    • Over-Pressure Suppresses Ultrasonic-Induced Drug Uptake 

      Stringham, S. Briant; Viskovska, Maria A.; Richardson, Eric S.; Ohmine, Seiga; Husseini, Ghaleb; Murray, Byron K.; Pitt, William G. (Elseviser, 2008)
      Ultrasound (US) is used to enhance and target delivery of drugs and genes to cancer tissues. The present study further examines the role of acoustic cavitation in US-induced permeabilization of cell membranes and subsequent ...