Browsing Department of Chemical and Biological Engineering by Subject "Active targeting"

Now showing items 1-4 of 4

    • Dual-Targeting and Stimuli-Triggered Liposomal Drug Delivery in Cancer Treatment 

      AlSawaftah, Nour Majdi; Pitt, William G.; Husseini, Ghaleb (American Chemical Society, 2021)
      The delivery of chemotherapeutics to solid tumors using smart drug delivery systems (SDDSs) takes advantage of the unique physiology of tumors (i.e., disordered structure, leaky vasculature, abnormal extracellular matrix ...

    • Liposomes in Active, Passive and Acoustically-Triggered Drug Delivery 

      Al Basha, Sara; Salkho, Najla; Dalibalta, Sarah; Husseini, Ghaleb (Bentham Science Publishers, 2019)
      Cancer has become one of the most deadly noncommunicable diseases globally. Several modalities used to treat cancer patients exist today yet many have failed to prove high efficacy with low side effects. The most common ...

    • Targeting the Folate Receptor: Effects of Conjugating Folic Acid to DOX Loaded Polymeric Micelles 

      Elkhodiry, Mohamed A.; Husseini, Ghaleb; Velluto, Diana (Bentham Science Publishers, 2016)
      In this paper, we report on a potential cancer drug delivery system that utilizes the ligand targeting of the folate receptor. Our drug delivery system consists of Pluronic-P105 micelles, targeted with folic acid moieties. ...

    • Ultrasound Triggering of Liposomal Nanodrugs for Cancer Therapy: A Review 

      Bahutair, Wafa N.; Abuwatfa, Waad Hussein; Husseini, Ghaleb (MDPI, 2022)
      Efficient conventional chemotherapy is limited by its nonspecific nature, which causes severe systemic toxicity that can lead to patient discomfort and low therapeutic efficacy. The emergence of smart drug delivery systems ...