Browsing by Author "117f79ae-150c-4314-8810-33e5da82e6a4"

Now showing items 1-8 of 8

    • The effect of pegylation and targeting moieties on the ultrasound-mediated drug release from liposomes 

      Awad, Nahid S.; Paul, Vinod; Mahmoud, Mohamad; AlSawaftah, Nour Majdi; Kawak, Paul S.; Al-Sayah, Mohammad; Husseini, Ghaleb (ACS Publications, 2019)
      The use of targeted liposomes encapsulating chemotherapy drugs enhances the specific targeting of cancer cells, thus, reducing the side effects of these agents and providing a more patient-friendly treatment. Targeted ...

    • Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release 

      Ahmed, Salma E.; Awad, Nahid S.; Paul, Vinod; Moussa, Hesham Gamal; Husseini, Ghaleb (Bentham Science Publishers, 2018)
      Conventional chemotherapeutics lack the specificity and controllability, thus may poison healthy cells while attempting to kill cancerous ones. Newly developed nano-drug delivery systems have shown promise in delivering ...

    • Modeling of Anti-cancer Drug Release Kinetics from Liposomes and Micelles: A review 

      AlSawaftah, Nour Majdi; Paul, Vinod; Awad, Nahid S.; Husseini, Ghaleb (Institute of Electrical and Electronics Engineers, 2021)
      Nanocarriers, such as liposomes and micelles, were developed to enhance the delivery of therapeutic drugs to malignant tissues. Internal or external stimuli can be applied to achieve spatiotemporal controlled release from ...

    • pH and ultrasound dual-responsive drug delivery system based on PEG–folate-functionalized Iron-based metal–organic framework for targeted doxorubicin delivery 

      Ahmed, Ahmed H.S; Karami, Abdollah; Sabouni, Rana; Husseini, Ghaleb; Paul, Vinod (Elsevier, 2021)
      In recent years, the use of metal–organic frameworks (MOFs) as drug nanocarriers has gained attention because of their extraordinary physical and chemical properties. In this work, dual-responsive iron-based MOFs were ...

    • Ultrasonically Controlled Albumin-conjugated Liposomes for Breast Cancer Therapy 

      Awad, Nahid S.; Paul, Vinod; Al-Sayah, Mohammad; Husseini, Ghaleb (Taylor and Francis Online, 2019)
      Targeted liposomes have high potentials in the specific and effective delivery of their loaded therapeutic agents to the tumor site. Once at the tumor site, it is important that these liposomes are triggered to release ...

    • Ultrasound-Mediated Cancer Therapeutics Delivery using Micelles and Liposomes: A Review 

      Mukhopadhyay, Debasmita; Sano, Catherine; AlSawaftah, Nour Majdi; Paul, Vinod; El-Awadi, Rafat; Husseini, Ghaleb (Bentham Science Publisher, 2021)
      Nanoparticles have proven promising as cancer theranostic tools. Nanoparticles are selective in nature, have reduced toxicity, and controllable drug release patterns making them ideal carriers for anticancer drugs. Numerous ...

    • Ultrasound-responsive Nanocarriers in Cancer Treatment: a review 

      Awad, Nahid S.; Paul, Vinod; Haar, Gail ter; Allen, Theresa M.; Pitt, William G.; AlSawaftah, Nour Majdi; Husseini, Ghaleb (American Chemical Society, 2021)
      The safe and effective delivery of anticancer agents to diseased tissues is one of the significant challenges in cancer therapy. Conventional anticancer agents are generally cytotoxins with poor pharmacokinetics and ...

    • Ultrasound‑triggered herceptin liposomes for breast cancer therapy 

      Elamir, Amal; Ajith, Saniha Aysha; AlSawaftah, Nour Majdi; Abuwatfa, Waad Hussein; Mukhopadhyay, Debasmita; Paul, Vinod; Al-Sayah, Mohammad; Awad, Nahid S.; Husseini, Ghaleb (Nature, 2021)
      The functionalization of liposomes with monoclonal antibodies is a potential strategy to increase the specificity of liposomes and reduce the side-effects associated with chemotherapeutic agents. The active targeting of ...