Browsing by Author "4c26cb28-9fdc-45ec-be3e-6040882c2ca0"
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Comparing microbubble cavitation at 500 kHz and 70 kHz related to micellar drug delivery using ultrasound
Diaz de la Rosa, Mario A.; Husseini, Ghaleb; Pitt, William G. (Elsevier, 2013)We have previously reported that ultrasonic drug release at 70 kHz was found to correlate with the presence of subharmonic emissions. No evidence of drug release or of the subharmonic emissions were detected in experiments ... -
Kinetics of acoustic release of doxorubicin from stabilized and unstabilized micelles and the effect of temperature
Husseini, Ghaleb; Diaz de la Rosa, Mario A.; AlAqqad, Emad O.; Al Mamary, Saif; Kadimati, Yaman; Al Baik, Abdullah; Pitt, William G. (Elsevier, 2011)Ultrasound is being investigated as a trigger mechanism to deliver high concentrations of chemotherapy drugs to cancerous tissues using polymeric micelles. In this paper, we examined the kinetics of acoustic release of ... -
Mathematical modeling of microbubble cavitation at 70 kHz and the importance of the subharmonic in drug delivery from micelles
Diaz de la Rosa, Mario A.; Husseini, Ghaleb; Pitt, William G. (Elsevier, 2013)In order to gain insight into the experimental observation of ultrasound-induced release of drugs from micelles, we modeled the dynamic oscillations of a 10-μm-diameter bubble insonated at 70 kHz. The Parlitz modification ... -
Release of Doxorubicin from Unstabilized and Stabilized Micelles Under the Action of Ultrasound
Husseini, Ghaleb; Diaz de la Rosa, Mario A.; Gabuji, Tasneem; Zeng, Yi; Christensen, Douglas A.; Pitt, William G. (American Scientific Publishers, 2007)Polymeric micelles are being investigated as chemotherapy drug delivery carriers using ultrasound as a trigger mechanism. The aim of this paper is to measure the release of Doxorubicin (Dox) from the core of unstabilized ...