Now showing items 21-32 of 32

    • Redox-Responsive Drug Delivery Systems: A Chemical Perspective 

      Abed, Heba; Abuwatfa, Waad Hussein; Husseini, Ghaleb (MDPI, 2022)
      With the widespread global impact of cancer on humans and the extensive side effects associated with current cancer treatments, a novel, effective, and safe treatment is needed. Redoxresponsive drug delivery systems (DDSs) ...
    • The role of cavitation in acoustically activated drug delivery 

      Husseini, Ghaleb; Diaz de la Rosa, Mario A.; Richardson, Eric S.; Christensen, Douglas A.; Pitt, William G. (Elsevier Science Direct, 2005)
      Pluronic P105 micelles are potential candidates as chemotherapy drug delivery vehicles using ultrasonic stimulation as a release trigger. Acoustic power has been previously shown to release two anthracycline agents from ...
    • Ultrasonic Drug Delivery Using Micelles and Liposomes 

      Martins, Ana M.; Ahmed, Salma E.; Vitor, Rute F.; Husseini, Ghaleb (Springer, 2016)
      The encapsulation of drugs in nanocarriers revolutionized research in drug delivery, especially in cancer chemotherapeutics. Several nanosystems have been developed including liposomes, polymeric micelles, dendrimers, solid ...
    • Ultrasonic-Activated Micellar Drug Delivery for Cancer Treatment 

      Husseini, Ghaleb; Pitt, William G. (Wiley InterSciences, 2008)
      The use of nanoparticles and ultrasound in medicine continues to evolve. Great strides have been made in the areas of producing micelles, nanoemulsions, and solid nanoparticles that can be used in drug delivery. An effective ...
    • Ultrasonically Controlled Albumin-conjugated Liposomes for Breast Cancer Therapy 

      Awad, Nahid S.; Paul, Vinod; Al-Sayah, Mohammad; Husseini, Ghaleb (Taylor and Francis Online, 2019)
      Targeted liposomes have high potentials in the specific and effective delivery of their loaded therapeutic agents to the tumor site. Once at the tumor site, it is important that these liposomes are triggered to release ...
    • Ultrasonically triggered drug delivery: Breaking the barrier 

      Husseini, Ghaleb; Pitt, William G.; Martins, Ana M. (Elsevier, 2014)
      The adverse side-effects of chemotherapy can be minimized by delivering the therapeutics in time and space to only the desired target site. Ultrasound offers one fairly non-invasive method of accomplishing such precise ...
    • Ultrasound in drug and gene delivery 

      Pitt, William G.; Husseini, Ghaleb (Elsevier, 2008)
      In this issue, we present the current applications and future prospects of ultrasound in various aspects of drug and gene delivery. There are many advantages to ultrasound that make it ideal for the delivery of therapeutics ...
    • Ultrasound-Mediated Cancer Therapeutics Delivery using Micelles and Liposomes: A Review 

      Mukhopadhyay, Debasmita; Sano, Catherine; AlSawaftah, Nour Majdi; Paul, Vinod; El-Awadi, Rafat; Husseini, Ghaleb (Bentham Science Publisher, 2021)
      Nanoparticles have proven promising as cancer theranostic tools. Nanoparticles are selective in nature, have reduced toxicity, and controllable drug release patterns making them ideal carriers for anticancer drugs. Numerous ...
    • Ultrasound-responsive Nanocarriers in Cancer Treatment: a review 

      Awad, Nahid S.; Paul, Vinod; Haar, Gail ter; Allen, Theresa M.; Pitt, William G.; AlSawaftah, Nour Majdi; Husseini, Ghaleb (American Chemical Society, 2021)
      The safe and effective delivery of anticancer agents to diseased tissues is one of the significant challenges in cancer therapy. Conventional anticancer agents are generally cytotoxins with poor pharmacokinetics and ...
    • Ultrasound-triggered Immunotherapy for Cancer Treatment: An Update 

      Mukhopadhyay, Debasmita; Ahmed, Amal Elsadig Elamir; Sano, Catherine; Awad, Nahid S.; AlSawaftah, Nour Majdi; Husseini, Ghaleb (Bentham, 2021)
    • Ultrasound-triggered Release from Micelles 

      Pitt, William G.; Husseini, Ghaleb; Kherbeck, Laura (Royal Society of Chemistry, 2013)
    • Ultrasound‑triggered herceptin liposomes for breast cancer therapy 

      Elamir, Amal; Ajith, Saniha Aysha; AlSawaftah, Nour Majdi; Abuwatfa, Waad Hussein; Mukhopadhyay, Debasmita; Paul, Vinod; Al-Sayah, Mohammad; Awad, Nahid S.; Husseini, Ghaleb (Nature, 2021)
      The functionalization of liposomes with monoclonal antibodies is a potential strategy to increase the specificity of liposomes and reduce the side-effects associated with chemotherapeutic agents. The active targeting of ...