Browsing by College/Dept "Dana Gas Endowed Chair for Chemical Engineering"
Now showing items 1-20 of 26
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Acoustically-Activated Liposomal Nanocarriers to Mitigate the Side Effects of Conventional Chemotherapy with a Focus on Emulsion-Liposomes
(MDPI, 2023)To improve currently available cancer treatments, nanomaterials are employed as smart drug delivery vehicles that can be engineered to locally target cancer cells and respond to stimuli. Nanocarriers can entrap chemotherapeutic ... -
Biomedical Applications of Metal−Organic Frameworks for Disease Diagnosis and Drug Delivery: A Review
(MDPI, 2021)Metal−organic frameworks (MOFs) are a novel class of porous hybrid organic−inorganic materials that have attracted increasing attention over the past decade. MOFs can be used in chemical engineering, materials science, and ... -
A Comparative Analysis of Numerical Methods for Solving the Leaky Fire and Integrate Model
(MDPI, 2023)The human nervous system is one of the most complex systems of the human body. Understanding its behavior is crucial in drug discovery and developing medical devices. One approach to understanding such a system is to model ... -
A Comprehensive Review on Membrane Fouling: Mathematical Modelling, Prediction, Diagnosis, and Mitigation
(MDPI, 2021)Membrane-based separation has gained increased popularity over the past few decades, particularly reverse osmosis (RO). A major impediment to the improved performance of membrane separation processes, in general, is membrane ... -
Comprehensive Study of a Diabetes Mellitus Mathematical Model Using Numerical Methods with Stability and Parametric Analysis
(MDPI, 2023-01-04)Diabetes is sweeping the world as a silent epidemic, posing a growing threat to public health. Modeling diabetes is an effective method to monitor the increasing prevalence of diabetes and develop cost-effective strategies ... -
Dual-Targeting and Stimuli-Triggered Liposomal Drug Delivery in Cancer Treatment
(American Chemical Society, 2021)The delivery of chemotherapeutics to solid tumors using smart drug delivery systems (SDDSs) takes advantage of the unique physiology of tumors (i.e., disordered structure, leaky vasculature, abnormal extracellular matrix ... -
Effect of High-Frequency Ultrasound on Targeted Liposomes
(American Scientific Publishers, 2022)Delivering highly toxic drugs inside a safe carrier to tumors while achieving a controlled and effective drug release at the targeted sites represents an attractive approach to enhance drug efficiency while reducing its ... -
Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review
(MDPI, 2022)Doxorubicin (DOX) is one of the most widely used anthracycline anticancer drugs due to its high efficacy and evident antitumoral activity on several cancer types. However, its effective utilization is hindered by the adverse ... -
Gold-Nanoparticle Hybrid Nanostructures for Multimodal Cancer Therapy
(MDPI, 2022)With the urgent need for bio-nanomaterials to improve the currently available cancer treatments, gold nanoparticle (GNP) hybrid nanostructures are rapidly rising as promising multimodal candidates for cancer therapy. Gold ... -
In Vitro Evaluation of Ultrasound Effectiveness in Controlling Doxorubicin Release from Albumin-Conjugated Liposomes
(American Scientific Publishers, 2022)Functionalized liposomes are among the most promising antineoplastic agents delivery vehicles. Contemporaneous to their accretion at the tumor site, they need to be potentiated to release their cargo using a suitable ... -
The Kinetics of Calcein Release from Mixed Targeted Liposomes Using Ultrasound
(American Scientific Publishers, 2022)Site-specific delivery of chemotherapeutics using actively targeted-stimuli-responsive liposomes is a promising approach to enhance the therapeutic efficiency of anti-cancer drugs while reducing the associated undesirable ... -
Modeling of Anti-cancer Drug Release Kinetics from Liposomes and Micelles: A review
(Institute of Electrical and Electronics Engineers, 2021)Nanocarriers, such as liposomes and micelles, were developed to enhance the delivery of therapeutic drugs to malignant tissues. Internal or external stimuli can be applied to achieve spatiotemporal controlled release from ... -
Modeling of Drug Release Kinetics from Stimuli- Responsive Micelles and Liposomes: A review
(IEEE, 2021)Nanocarriers such as micelles and liposomes were developed to enhance the delivery of therapeutic drugs to tumors. Internal or external stimuli can be applied to achieve spatiotemporal controlled release from these carriers. ... -
Modeling of the In Vitro Release Kinetics of Sonosensitive Targeted Liposomes
(MDPI, 2022-12-05)Targeted liposomes triggered by ultrasound are a promising drug delivery system as they potentially improve the clinical outcomes of chemotherapy while reducing associated side effects. In this work, a comprehensive model ... -
pH-Responsive Nanocarriers in Cancer Therapy
(MDPI, 2022)A number of promising nano-sized particles (nanoparticles) have been developed to conquer the limitations of conventional chemotherapy. One of the most promising methods is stimuli-responsive nanoparticles because they ... -
Photo-Induced Drug Release from Polymeric Micelles and Liposomes: Phototriggering Mechanisms in Drug-Delivery Systems
(MDPI, 2022)Chemotherapeutic drugs are highly effective in treating cancer. However, the side effects associated with this treatment lower the quality of life of cancer patients. Smart nanocarriers are able to encapsulate these drugs ... -
Recent Advances in Nanoparticle-Based Co-Delivery Systems for Cancer Therapy
(MDPI, 2022-08)Cancer therapies have advanced tremendously throughout the last decade, yet multiple factors still hinder the success of the different cancer therapeutics. The traditional therapeutic approach has been proven insufficient ... -
Redox-Responsive Drug Delivery Systems: A Chemical Perspective
(MDPI, 2022)With the widespread global impact of cancer on humans and the extensive side effects associated with current cancer treatments, a novel, effective, and safe treatment is needed. Redoxresponsive drug delivery systems (DDSs) ... -
A Review on Membrane Biofouling: Prediction, Characterization, and Mitigation
(MDPI, 2022-12-15)Water scarcity is an increasing problem on every continent, which instigated the search for novel ways to provide clean water suitable for human use; one such way is desalination. Desalination refers to the process of ... -
Thermosensitive Polymers and Thermo-Responsive Liposomal Drug Delivery Systems
(MDPI, 2022)Temperature excursions within a biological milieu can be effectively used to induce drug release from thermosensitive drug-encapsulating nanoparticles. Oncological hyperthermia is of particular interest, as it is proven ...
