Browsing by Subject "Cancer"
Now showing items 1-20 of 31
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Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment
(2016-01)Chemotherapy is frequently used in cancer treatment. However, side effects associated with this type of treatment are often detrimental to the patient's health. This thesis discusses a novel approach of delivering a cytotoxic ... -
Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs)
(Bentham Science Publishers, 2017)Cancer is the uncontrolled growth of cells in the body and is considered as one of the major causes of death globally. There are several cytotoxic chemotherapeutic agents used to treat cancer including methotrexate, ... -
Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs) and Ultrasound.
(2016-05)Cancer is defined as the uncontrolled growth of abnormal cells. Although billions of dollars have been spent on cancer research to develop its treatments, cancer still remains a major illness for mankind, partly due to the ... -
Antitumour Activities of Selected Pure Compounds Identified from the Serum of Crocodylus porosus, Malayopython reticulatus, Varanus salvator and Cuora kamaroma amboinensis
(Asian Pacific Organization for Cancer Prevention, 2021)Objectives: Here we determined antitumour effects of purified compounds such as Valdecoxib, Rofecoxib, L-Methionine and Artocarpin against cancer cell lines. Methods: Using purified compounds, assays were performed to ... -
Bioluminescence Imaging Applications in Cancer: A Comprehensive Review
(IEEE, 2020)Bioluminescence imaging (BLI), an optical preclinical imaging modality, is an invaluable imaging modality due to its low-cost, high throughput, fast acquisition times, and functional imaging capabilities. BLI is being ... -
Carbohydrate-Functionalized Liposomes In Cancer Therapy
(Bentham Science, 2020)Existing cancer treatments are often accompanied by adverse side effects that can greatly reduce the quality of life of cancer patients; this sets the platform for the development and application of nanocarrier-based ... -
Doxorubicin-encapsulated Albumin liposomes with acoustic triggering for cancer treatment
(2019-05)With cancer being the leading cause of death worldwide, increasing economic and social resources are being directed by researchers and healthcare professionals to treat the disease, or at least provide palliative care to ... -
Drug Delivery Systems Based on Polymeric Micelles and Ultrasound: A Review
(Bentham Science Publishers, 2016)Anti-neoplastic drugs used for cancer treatment often produce damage to healthy cells, leading to severe side effects in patients undergoing chemotherapy. The encapsulation of these agents in nanoparticles reduces the ... -
Dual-Targeting and Stimuli-Triggered Liposomal Drug Delivery in Cancer Treatment
(American Chemical Society, 2021)The delivery of chemotherapeutics to solid tumors using smart drug delivery systems (SDDSs) takes advantage of the unique physiology of tumors (i.e., disordered structure, leaky vasculature, abnormal extracellular matrix ... -
The Effect of Ultrasound on the Drug Delivery of RGD-Targeted Liposomes
(2018-05)Approaches used to treat cancer, with the most prominent being chemotherapy, have detrimental effects on patients’ health. Doxorubicin, a chemotherapeutic agent, alters normal cellular functions and can cause many fatal ... -
The Effects of cRGD Targeting Liposomes When Paired With Ultrasonic Waves on Drug Delivery
(2021-04)Cancer is a leading fatal disease, which has the ability to grow uncontrollably and spread throughout the body of the patient. Several approaches have been used to treat cancer, chemotherapy being the most common treatment ... -
Immunoliposomes: Synthesis, Structure, and Their Potential as Drug Delivery Carriers
(Bentham Science, 2020)Immunoliposomes have emerged as attractive drug targeting vehicles for cancer treatment. This review presents the recent advances in the design of immunoliposomes encapsulating a variety of chemotherapeutic agents. We ... -
Investigating and Modeling the Acoustic Release of Doxorubicin from Folate Targeted Micelles
(2012-06)To minimize the adverse side effects of conventional chemotherapy, a targeted micellar drug carrier was investigated that retains hydrophobic drugs in its core and then releases the drug via ultrasound. This thesis reports ... -
Investigation and Mathematical Modeling of Acoustic Release of Doxorubicin from Micelles
(2020-05)Given the growing concern over the increasing number of people diagnosed with cancer and the high prevalence of unwanted side effects associated with chemotherapy on healthy tissues, this thesis aims to provide better, ... -
Liposomal drug release using ultrasound and modeling release dynamics for model predictive controller design
(2015-06)Chemotherapy is widely used for cancer treatment; however, it causes unwanted side effects in patients such as fatigue, weight loss, pain, hair fall and nausea. Those side effects are due to the fact that most of the ... -
Lipsome-coated metal organic frameworks as a new drug nanocarrier
(2019-12)Cancer has emerged to become one of the predominant diseases ever known to humanity, with chemotherapeutic agents as leading methods for treating it. However, this blind-sighted treatment method that targets all cells; ... -
Microwave Triggered Release of Doxorubicin from Metal-organic Frameworks
(2022-11)Metal-Organic Frameworks (MOFs) are ideal candidates for a variety of applications based on their remarkable properties such as high surface area and porosity. A substantial number of studies have been conducted to examine ... -
Modeling the Effects of Chemotherapy and Immunotherapy on Tumor Growth
(American Scientific Publishers, 2021)Mathematical modeling has been used to simulate the interaction of chemotherapy and immunotherapy drugs intervention with the dynamics of tumor cells growth. This work studies the interaction of cells in the immune system, ... -
Multi-Model Investigation and Adaptive Estimation of the Acoustic Release of a Model Drug From Liposomes
(IEEE, 2019)This paper researches a suitable mathematical model that can reliably predict the release of a model drug (namely calcein) from biologically targeted liposomal nanocarriers triggered by ultrasound. Using mathematical models, ... -
pH-Responsive Nanocarriers in Cancer Therapy
(MDPI, 2022)A number of promising nano-sized particles (nanoparticles) have been developed to conquer the limitations of conventional chemotherapy. One of the most promising methods is stimuli-responsive nanoparticles because they ...
