Search
Now showing items 1-10 of 25
The Use of Transferrin and Ultrasound in Cancer Treatment
(2019-05)
Site-specific drug delivery represents an attractive approach in cancer treatment to reduce the undesirable side-effects of anticancer therapeutics and increase the accumulation of drugs at tumor sites. Surface modification ...
Targeting Breast Cancer Using Hyaluronic Acid-Conjugated Liposomes Triggered with Ultrasound
(American Science Publishers, 2021)
The successful targeting of tumors can be achieved by conjugating targeting moieties to nanoparticles. These modifications allow nannocarriers to achieve greater targeting specificity through binding to specific receptors ...
Immunoliposomes: Synthesis, Structure, and Their Potential as Drug Delivery Carriers
(Bentham Science, 2020)
Immunoliposomes have emerged as attractive drug targeting vehicles for cancer treatment. This review presents the recent advances in the design of immunoliposomes encapsulating a variety of chemotherapeutic agents. We ...
Carbohydrate-Functionalized Liposomes In Cancer Therapy
(Bentham Science, 2020)
Existing cancer treatments are often accompanied by adverse side effects that can greatly reduce the quality of life of cancer patients; this sets the platform for the development and application of nanocarrier-based ...
Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review
(American Scientific Publishers, 2020)
The use of ultrasound as a medical diagnostic tool began in the 1940s. Ever since, the medical applications of ultrasound have included imaging, tumor ablation, and lithotripsy; however, an ever-increasing body of literature ...
Identification of Novel MicroRNAs as Promising Therapeutics for SARS-CoV-2 by Regulating the EGFR-ADAM17 Axis: An In Silico Analysis
(American Chemical Society, 2021)
Cancer patients contracting SARS-CoV-2 encounter additional challenges due to inflammatory bursts and lymphopenia, which may aggravate breast cancer prognosis. In this in-silico analysis, we identified the potential of ...
Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis
(American Chemical Society, 2021)
In this study, we investigated the interactions between SARS-CoV-2 and miRNAs associated with lung cancer using bioinformatic approaches. A special focus was placed on TMPRSS2 and lung cancer progression pathways involving ...
A Comprehensive Review on Membrane Fouling: Mathematical Modelling, Prediction, Diagnosis, and Mitigation
(MDPI, 2021)
Membrane-based separation has gained increased popularity over the past few decades, particularly reverse osmosis (RO). A major impediment to the improved performance of membrane separation processes, in general, is membrane ...
Transferrin‑modifed liposomes triggered with ultrasound to treat HeLa cells
(Nature, 2021)
Targeted liposomes are designed to target specific receptors overexpressed on the surfaces of cancer cells. This technique ensures site-specific drug delivery to reduce undesirable side effects while enhancing the efficiency ...
Dual-Targeting and Stimuli-Triggered Liposomal Drug Delivery in Cancer Treatment
(American Chemical Society, 2021)
The delivery of chemotherapeutics to solid tumors using smart drug delivery systems (SDDSs) takes advantage of the unique physiology of tumors (i.e., disordered structure, leaky vasculature, abnormal extracellular matrix ...