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    Drug delivery in pluronic micelles: effect of high-frequency ultrasound on drug release from micelles and intracellular uptake 

    Marin, Alexander; Sun, Hao; Husseini, Ghaleb; Pitt, William G.; Christensen, Douglas A.; Rapoport, Natalya Y. (Elsevier, 2002)
    The effect of high-frequency ultrasound on doxorubicin (DOX) release from Pluronic micelles and intracellular DOX uptake was studied for promyelocytic leukemia HL-60 cells, ovarian carcinoma drug-sensitive and multidrug-resistant ...
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    Kinetics of ultrasonic release of doxorubicin from pluronic P105 micelles 

    Husseini, Ghaleb; Rapoport, Natalya Y.; Christensen, Douglas A.; Pruitt, John D.; Pitt, William G. (Elsevier, 2001)
    The aim of this research was to measure and model the kinetics of acoustic release and subsequent re-encapsulation of Doxorubicin (DOX) from Pluronic P105 micelles. A fluorescence detection ultrasound exposure chamber was ...
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    DNA damage induced by micellar-delivered doxorubicin and ultrasound: comet assay study 

    Husseini, Ghaleb; El-Fayoumi, Refaat I.; O'Neill, Kim L.; Rapoport, Natalya Y.; Pitt, William G. (Elsevier, 2000)
    To minimize adverse side effects of chemotherapy, we have developed a micellar drug carrier that retains hydrophobic drugs, and then releases the drug by ultrasonic stimulation. This study investigated the DNA damage induced ...
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    Ultrasonic release of doxorubicin from Pluronic P105 micelles stabilized with an interpenetrating network of N,N diethylacrylamide 

    Husseini, Ghaleb; Christensen, Douglas A.; Rapoport, Natalya Y.; Pitt, William G. (Elsevier, 2002)
    Pluronic P105 micelles sequester hydrophobic drugs and release them upon insonation with low frequency ultrasound; however these micelles dissolve relatively quickly upon dilution. The objective of this research was to ...
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    Factors affecting acoustically triggered release of drugs from polymeric micelles 

    Husseini, Ghaleb; Myrup, Gregg D.; Pitt, William G.; Christensen, Douglas A.; Rapoport, Natalya Y. (Elsevier, 2000)
    A custom ultrasonic exposure chamber with real-time fluorescence detection was used to measure acoustically-triggered drug release from Pluronic P-105 micelles under continuous wave (CW) or pulsed ultrasound in the frequency ...

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    AuthorHusseini, Ghaleb (5)Pitt, William G. (5)
    Rapoport, Natalya Y. (5)
    Christensen, Douglas A. (4)El-Fayoumi, Refaat I. (1)Marin, Alexander (1)Myrup, Gregg D. (1)O'Neill, Kim L. (1)Pruitt, John D. (1)Sun, Hao (1)Subject
    Doxorubicin (5)
    Micellar drug delivery (4)Ultrasound (3)Pluronic (2)A2780 cells (1)A2780/ADR cells (1)Comet assay (1)Drug delivery (1)Fluorescence Measurement (1)Fluorescence measurement (1)... View MoreDate Issued2000 (2)2002 (2)2001 (1)Has File(s)
    Yes (5)

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