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Whole Organism Model to Study Molecular Mechanisms of Differentiation and Dedifferentiation
(MDPI, 2020)
Cancer recurrence has remained a significant challenge, despite advances in therapeutic approaches. In part, this is due to our incomplete understanding of the biology of cancer stem cells and the underlying molecular ...
Liposomal drug release using ultrasound and modeling release dynamics for model predictive controller design
(2015-06)
Chemotherapy is widely used for cancer treatment; however, it causes unwanted side effects in patients such as fatigue, weight loss, pain, hair fall and nausea. Those side effects are due to the fact that most of the ...
Lipsome-coated metal organic frameworks as a new drug nanocarrier
(2019-12)
Cancer has emerged to become one of the predominant diseases ever known to humanity, with chemotherapeutic agents as leading methods for treating it. However, this blind-sighted treatment method that targets all cells; ...
Preparation of albumin-targeted liposomes and the study of their release characteristics using ultrasound
(2016-01)
The main objective of this thesis was to investigate the enhancement of drug delivery using targeted liposomes triggered by ultrasound. In this thesis, a thorough literature review on cancer and drug delivery systems ...
Investigating and Modeling the Acoustic Release of Doxorubicin from Folate Targeted Micelles
(2012-06)
To minimize the adverse side effects of conventional chemotherapy, a targeted micellar drug carrier was investigated that retains hydrophobic drugs in its core and then releases the drug via ultrasound. This thesis reports ...
Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs) and Ultrasound.
(2016-05)
Cancer is defined as the uncontrolled growth of abnormal cells. Although billions of dollars have been spent on cancer research to develop its treatments, cancer still remains a major illness for mankind, partly due to the ...
Investigation and Mathematical Modeling of Acoustic Release of Doxorubicin from Micelles
(2020-05)
Given the growing concern over the increasing number of people diagnosed with cancer and the high prevalence of unwanted side effects associated with chemotherapy on healthy tissues, this thesis aims to provide better, ...
Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer
(2018-12)
Cancer is one of the deadliest diseases in this era. Since conventional treatment has many side effects, its use is limited, which augments the need for new smart drug delivery systems, such as nanocarriers, capable of ...
Ultrasonic-Activated Micellar Drug Delivery for Cancer Treatment
(Wiley InterSciences, 2008)
The use of nanoparticles and ultrasound in medicine continues to evolve. Great strides have been made in the areas of producing micelles, nanoemulsions, and solid nanoparticles that can be used in drug delivery. An effective ...
Bioluminescence Imaging Applications in Cancer: A Comprehensive Review
(IEEE, 2020)
Bioluminescence imaging (BLI), an optical preclinical imaging modality, is an invaluable imaging modality due to its low-cost, high throughput, fast acquisition times, and functional imaging capabilities. BLI is being ...