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Now showing items 21-29 of 29
Hybrid Liposome/Metal–Organic Framework as a Promising Dual-Responsive Nanocarriers for Anticancer Drug Delivery
(Elsevier, 2022)
In this work, liposome-coated iron (III) benzene-1,3,5-tricarboxylate (Fe-BTC) metal–organic framework is examined as a promising pH/Ultrasound dual-responsive nanocarriers for doxorubicin (DOX) delivery. The successful ...
Combined and Single Doxorubicin/Naproxen Drug Loading and Dual-Responsive pH/Ultrasound Release from Flexible Metal-Organic Framework Nanocarriers
(American Scientific Publishers, 2022)
In this study, the flexible aluminum-based MIL-53(Al) metal-organic framework was loaded with doxorubicin (DOX) and naproxen (NAP) and was examined as a promising pH/ultrasound dual-responsive drug delivery system. The two ...
Microwave Triggered Release of Doxorubicin from Metal-organic Frameworks
(2022-11)
Metal-Organic Frameworks (MOFs) are ideal candidates for a variety of applications based on their remarkable properties such as high surface area and porosity. A substantial number of studies have been conducted to examine ...
Facile Ultrasound-Triggered Release of Calcein and Doxorubicin from Iron-Based Metal-Organic Frameworks
(American Scientific Publishers, 2020)
Metal-organic frameworks (MOFs) are promising new nanocarriers with potential use in anticancer drug delivery. However, there is a scarcity of studies on the uptake and release of guest molecules associated with MOF ...
Further investigation of the mechanism of Doxorubicin release from P105 micelles using kinetic models
(Elsevier, 2006)
The kinetics of the release of Doxorubicin from Pluronic P105 micelles during ultrasonication and its subsequent re-encapsulation upon cessation of insonation were investigated. Four mechanisms are proposed to explain the ...
Investigating and Modeling the Acoustic Release of Doxorubicin from Folate Targeted Micelles
(2012-06)
To minimize the adverse side effects of conventional chemotherapy, a targeted micellar drug carrier was investigated that retains hydrophobic drugs in its core and then releases the drug via ultrasound. This thesis reports ...
The role of cavitation in acoustically activated drug delivery
(Elsevier Science Direct, 2005)
Pluronic P105 micelles are potential candidates as chemotherapy drug delivery vehicles using ultrasonic stimulation as a release trigger. Acoustic power has been previously shown to release two anthracycline agents from ...
The Comet Assay to Determine the Mode of Cell Death for the Ultrasonic Delivery of Doxorubicin to Human Leukemia (HL-60 Cells) from Pluronic P105 Micelles
(Adenine Press, 2005)
This notes examines the mode of cell death of HL-60 cells exposed to 70 kHz and 1.3 W/cm2 ultrasound in the presence of 1% Pluronic P105 and 1.67 μg/ml doxorubicin (Dox). The cells were ultrasonicated for 30, 60, and 120 ...
Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release
(Bentham Science Publishers, 2018)
Conventional chemotherapeutics lack the specificity and controllability, thus may poison healthy cells while attempting to kill cancerous ones. Newly developed nano-drug delivery systems have shown promise in delivering ...