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Synthesis of Metal-Organic Framework from Iron Nitrate and 2,6-Naphthalenedicarboxylic Acid and Its Application as Drug Carrier
(American Scientific Publishers, 2018)
Metal-organic frameworks (MOFs) are highly crystalline porous organic–inorganic materials that are comprised of metal salts and organic linkers. The common synthetic methodologies of MOFs include: solvothermal, microwave-assisted, ...
Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs)
(Bentham Science Publishers, 2017)
Cancer is the uncontrolled growth of cells in the body and is considered as one of the major causes of death globally. There are several cytotoxic chemotherapeutic agents used to treat cancer including methotrexate, ...
Facile Ultrasound-Triggered Release of Calcein and Doxorubicin from Iron-Based Metal-Organic Frameworks
(American Scientific Publishers, 2020)
Metal-organic frameworks (MOFs) are promising new nanocarriers with potential use in anticancer drug delivery. However, there is a scarcity of studies on the uptake and release of guest molecules associated with MOF ...
Green Nanotechnology—A Road Map to Safer Nanomaterials
(Woodhead Publishing, 2018)
Nanotechnology has remained at the forefront of scientific research for the past few decades due to its outstanding properties and associated applications. The unlimited potential of nanomaterials have already influenced ...
Recent Advances in Metal-Organic Frameworks as Anticancer Drug Delivery Systems: A Review
(Bentham, 2021)
Background: Metal-organic frameworks (MOFs), as attractive hybrid crystalline porous materials, are increasingly being investigated in biomedical applications owing to their exceptional properties, including high porosity, ...
Biomedical Applications of Metal−Organic Frameworks for Disease Diagnosis and Drug Delivery: A Review
(MDPI, 2021)
Metal−organic frameworks (MOFs) are a novel class of porous hybrid organic−inorganic materials that have attracted increasing attention over the past decade. MOFs can be used in chemical engineering, materials science, and ...
Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review
(MDPI, 2022)
Doxorubicin (DOX) is one of the most widely used anthracycline anticancer drugs due to its high efficacy and evident antitumoral activity on several cancer types. However, its effective utilization is hindered by the adverse ...
Toxicological impact of nanoparticles on human health: A review
(American Scientific Publishers, 2022)
Nanotechnology is a rapidly growing industry where nanomaterials are used in almost every field, including electronics, cosmetics, engineering, household products, biotechnology and medicine. Nanoparticles (NPs) have unique ...
Hybrid Liposome/Metal–Organic Framework as a Promising Dual-Responsive Nanocarriers for Anticancer Drug Delivery
(Elsevier, 2022)
In this work, liposome-coated iron (III) benzene-1,3,5-tricarboxylate (Fe-BTC) metal–organic framework is examined as a promising pH/Ultrasound dual-responsive nanocarriers for doxorubicin (DOX) delivery. The successful ...
Combined and Single Doxorubicin/Naproxen Drug Loading and Dual-Responsive pH/Ultrasound Release from Flexible Metal-Organic Framework Nanocarriers
(American Scientific Publishers, 2022)
In this study, the flexible aluminum-based MIL-53(Al) metal-organic framework was loaded with doxorubicin (DOX) and naproxen (NAP) and was examined as a promising pH/ultrasound dual-responsive drug delivery system. The two ...