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Measuring the Acoustic Release of a Chemotherapeutic Agent from Folate-Targeted Polymeric Micelles
(American Scientific Publishers, 2018)
In this paper, we compare the use of Bayesian filters for the estimation of release and reencapsulation rates of a chemotherapeutic agent (namely Doxorubicin) from nanocarriers in an acoustically activated drug release ...
Synergistic Nanomedicine: Passive, Active, and Ultrasound-Triggered Drug Delivery in Cancer Treatment
(American Scientific Publishers, 2015)
Nanocarriers are heavily researched as drug delivery vehicles capable of sequestering antineoplastic agents and then releasing their contents at the desired location. The feasibility of using such carriers stems from their ...
Stabilization of Pluronic P-105 Micelles with an Interpenetrating Network of N,N-Diethylacrylamide
(American Chemical Society, 2000)
N,N-Diethylacrylamide (NNDEA) was polymerized in the presence of Pluronic P-105 micelles. The polymerizations resulted in an interpenetrating network of poly(NNDEA) and P-105 that stabilized the micelles at concentrations ...
Targeting the Folate Receptor: Effects of Conjugating Folic Acid to DOX Loaded Polymeric Micelles
(Bentham Science Publishers, 2016)
In this paper, we report on a potential cancer drug delivery system that utilizes the ligand targeting of the folate receptor. Our drug delivery system consists of Pluronic-P105 micelles, targeted with folic acid moieties. ...
Ultrasound-induced doxorubicin release from folate-targeted and non-targeted P105 micelles: a modeling study
(De Gruyter, 2016)
The aim of this work is to study the kinetics of ultrasound (70 kHz) – using a kinetic model that takes into account cavitation events and drug re-encapsulation upon the cessation of the acoustic field. The simulation ...
Modeling of Drug Release Kinetics from Stimuli- Responsive Micelles and Liposomes: A review
(IEEE, 2021)
Nanocarriers such as micelles and liposomes were developed to enhance the delivery of therapeutic drugs to tumors. Internal or external stimuli can be applied to achieve spatiotemporal controlled release from these carriers. ...
Modeling of Anti-cancer Drug Release Kinetics from Liposomes and Micelles: A review
(Institute of Electrical and Electronics Engineers, 2021)
Nanocarriers, such as liposomes and micelles, were developed to enhance the delivery of therapeutic drugs to malignant tissues. Internal or external stimuli can be applied to achieve spatiotemporal controlled release from ...
Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review
(MDPI, 2022)
Doxorubicin (DOX) is one of the most widely used anthracycline anticancer drugs due to its high efficacy and evident antitumoral activity on several cancer types. However, its effective utilization is hindered by the adverse ...