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    Release of Doxorubicin from Unstabilized and Stabilized Micelles Under the Action of Ultrasound 

    Husseini, Ghaleb; Diaz de la Rosa, Mario A.; Gabuji, Tasneem; Zeng, Yi; Christensen, Douglas A.; Pitt, William G. (American Scientific Publishers, 2007)
    Polymeric micelles are being investigated as chemotherapy drug delivery carriers using ultrasound as a trigger mechanism. The aim of this paper is to measure the release of Doxorubicin (Dox) from the core of unstabilized ...
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    The role of cavitation in acoustically activated drug delivery 

    Husseini, Ghaleb; Diaz de la Rosa, Mario A.; Richardson, Eric S.; Christensen, Douglas A.; Pitt, William G. (Elsevier Science Direct, 2005)
    Pluronic P105 micelles are potential candidates as chemotherapy drug delivery vehicles using ultrasonic stimulation as a release trigger. Acoustic power has been previously shown to release two anthracycline agents from ...
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    Drug delivery in pluronic micelles: effect of high-frequency ultrasound on drug release from micelles and intracellular uptake 

    Marin, Alexander; Sun, Hao; Husseini, Ghaleb; Pitt, William G.; Christensen, Douglas A.; Rapoport, Natalya Y. (Elsevier, 2002)
    The effect of high-frequency ultrasound on doxorubicin (DOX) release from Pluronic micelles and intracellular DOX uptake was studied for promyelocytic leukemia HL-60 cells, ovarian carcinoma drug-sensitive and multidrug-resistant ...
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    Kinetics of ultrasonic release of doxorubicin from pluronic P105 micelles 

    Husseini, Ghaleb; Rapoport, Natalya Y.; Christensen, Douglas A.; Pruitt, John D.; Pitt, William G. (Elsevier, 2001)
    The aim of this research was to measure and model the kinetics of acoustic release and subsequent re-encapsulation of Doxorubicin (DOX) from Pluronic P105 micelles. A fluorescence detection ultrasound exposure chamber was ...
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    Degradation kinetics of stabilized Pluronic micelles under the action of ultrasound 

    Husseini, Ghaleb; Pitt, William G.; Christensen, Douglas A.; Dickinson, David J. (Elsevier, 2009)
    The majority of research in the area of acoustically-activated drug delivery from stabilized micelles has been focused on the rapid release of chemotherapy drugs from the core of such nano-carriers. Previous publications ...
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    Ultrasonic release of doxorubicin from Pluronic P105 micelles stabilized with an interpenetrating network of N,N diethylacrylamide 

    Husseini, Ghaleb; Christensen, Douglas A.; Rapoport, Natalya Y.; Pitt, William G. (Elsevier, 2002)
    Pluronic P105 micelles sequester hydrophobic drugs and release them upon insonation with low frequency ultrasound; however these micelles dissolve relatively quickly upon dilution. The objective of this research was to ...
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    Investigating the acoustic release of doxorubicin from targeted micelles 

    Husseini, Ghaleb; Velluto, Diana; Kherbeck, Laura; Pitt, William G.; Hubbell, Jeffrey A.; Christensen, Douglas A. (Elsevier, 2013)
    The main problem associated with the administration of anti-cancer medication is that the drug is delivered throughout the body causing undesirable side effects. Therefore, it is important to synthesize drug carriers capable ...
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    Factors affecting acoustically triggered release of drugs from polymeric micelles 

    Husseini, Ghaleb; Myrup, Gregg D.; Pitt, William G.; Christensen, Douglas A.; Rapoport, Natalya Y. (Elsevier, 2000)
    A custom ultrasonic exposure chamber with real-time fluorescence detection was used to measure acoustically-triggered drug release from Pluronic P-105 micelles under continuous wave (CW) or pulsed ultrasound in the frequency ...
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    Kinetics of Ultrasonic Drug Delivery from Targeted Micelles 

    Husseini, Ghaleb; Kherbeck, Laura; Pitt, William G.; Hubbell, Jeffrey A.; Christensen, Douglas A.; Velluto, Diana (American Scientific Publishers, 2015)
    To minimize the adverse side effects of conventional chemotherapy, a targeted micellar drug carrier was investigated that retains hydrophobic drugs in its core and then releases the drug via ultrasonic activation. This ...

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    Author
    Christensen, Douglas A. (9)
    Husseini, Ghaleb (9)
    Pitt, William G. (9)
    Rapoport, Natalya Y. (4)Diaz de la Rosa, Mario A. (2)Hubbell, Jeffrey A. (2)Kherbeck, Laura (2)Velluto, Diana (2)Dickinson, David J. (1)Gabuji, Tasneem (1)... View MoreSubjectDoxorubicin (7)Ultrasound (4)Micellar drug delivery (3)Drug release (2)Pluronic (2)Pluronic micelles (2)Pluronic P105 (2)Polymeric micelles (2)Stabilized micelles (2)70-kHz Ultrasound (1)... View MoreDate Issued2010 - 2015 (2)2000 - 2009 (7)Has File(s)Yes (9)

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