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dc.contributor.authorAbuwatfa, Waad Hussein
dc.contributor.authorAwad, Nahid S.
dc.contributor.authorPitt, William G.
dc.contributor.authorHusseini, Ghaleb
dc.date.accessioned2022-02-28T07:03:32Z
dc.date.available2022-02-28T07:03:32Z
dc.date.issued2022
dc.identifier.citationAbuwatfa, W.H.; Awad, N.S.; Pitt, W.G.; Husseini, G.A. Thermosensitive Polymers and Thermo-Responsive Liposomal Drug Delivery Systems. Polymers 2022, 14, 925. https://doi.org/10.3390/polym14050925en_US
dc.identifier.issn2073-4360
dc.identifier.urihttp://hdl.handle.net/11073/21642
dc.description.abstractTemperature excursions within a biological milieu can be effectively used to induce drug release from thermosensitive drug-encapsulating nanoparticles. Oncological hyperthermia is of particular interest, as it is proven to synergistically act to arrest tumor growth when combined with optimally-designed smart drug delivery systems (DDSs). Thermoresponsive DDSs aid in making the drugs more bioavailable, enhance the therapeutic index and pharmacokinetic trends, and provide the spatial placement and temporal delivery of the drug into localized anatomical sites. This paper reviews the fundamentals of thermosensitive polymers, with a particular focus on thermoresponsive liposomal-based drug delivery systems.en_US
dc.description.sponsorshipDana Gas Endowed Chair for Chemical Engineeringen_US
dc.description.sponsorshipAmerican University of Sharjahen_US
dc.description.sponsorshipSheikh Hamdan Award for Medical Sciencesen_US
dc.description.sponsorshipFriends of Cancer Patienten_US
dc.language.isoen_USen_US
dc.publisherMDPIen_US
dc.relation.urihttps://doi.org/10.3390/polym14050925en_US
dc.subjectHyperthermiaen_US
dc.subjectThermosensitivityen_US
dc.subjectLiposomesen_US
dc.subjectCritical solution temperatureen_US
dc.subjectLysolipidsen_US
dc.subjectPolymersen_US
dc.titleThermosensitive Polymers and Thermo-Responsive Liposomal Drug Delivery Systemsen_US
dc.typeArticleen_US
dc.typePeer-Revieweden_US
dc.typePublished versionen_US
dc.identifier.doi10.3390/polym14050925


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