dc.contributor.author | Salkho, Najla | |
dc.contributor.author | Turki, Renad | |
dc.contributor.author | O, Guessoum | |
dc.contributor.author | Martins, Ana M. | |
dc.contributor.author | Vitor, Rute F. | |
dc.contributor.author | Husseini, Ghaleb | |
dc.date.accessioned | 2024-04-18T06:18:12Z | |
dc.date.available | 2024-04-18T06:18:12Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Salkho NM, Turki RZ, Guessoum O, Martins AM, Vitor RF, Husseini GA. Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment. Curr Mol Med. 2017;17(10):668-688. doi: 10.2174/1566524018666180416100142. PMID: 29663885. | en_US |
dc.identifier.issn | 1566-5240 | |
dc.identifier.uri | http://hdl.handle.net/11073/25514 | |
dc.description.abstract | The initial uses of ultrasound waves in the medical field were limited to the thermal ablation of solid tumors and as a diagnostic tool. Recent advances at the preclinical stage have allowed the use of ultrasound as a powerful tool to improve drug delivery when the agent is administered encapsulated inside a nanoparticle. This spatial and temporal control of drug release, using a non-invasive modality, is a promising approach to decrease the side effects of conventional chemotherapy in cancer treatments, as it reduces the interaction of the anti-neoplastic agent with healthy tissues. In this review, we explain the physics of ultrasound, introduce and discuss several examples on the use of nanoparticles as drug carriers, with a focus on liposomes. Examples of in vitro and in vivo studies are presented and discussed. | en_US |
dc.description.sponsorship | American University of Sharjah | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Bentham Science | en_US |
dc.relation.uri | https://doi.org/10.2174/1566524018666180416100142 | en_US |
dc.subject | Cancer | en_US |
dc.subject | Anti-neoplastic agent | en_US |
dc.subject | Drug delivery | en_US |
dc.subject | Drug Release | en_US |
dc.subject | Liposomes | en_US |
dc.subject | Ultrasound | en_US |
dc.title | Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment | en_US |
dc.type | Article | en_US |
dc.type | Peer-Reviewed | en_US |
dc.type | Published version | en_US |
dc.identifier.doi | 10.2174/1566524018666180416100142 | |