College of Engineering (CEN)

Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes

Hamidu, Aisha; Pitt, William G.; Husseini, Ghaleb (MDPI, 2023)

Cancer is one of the leading causes of death worldwide. Because each person’s cancer may be unique, diagnosing and treating cancer is challenging. Advances in nanomedicine have made it possible to detect tumors and quickly ...

Transferrin-Targeted Liposomes in Glioblastoma Therapy: A Review

Kawak, Paul S.; AlSawaftah, Nour Majdi; Pitt, William G.; Husseini, Ghaleb (MDPI, 2026-08-26)

Glioblastoma (GBM) is a highly aggressive brain tumor, and its treatment is further complicated by the high selectivity of the blood–brain barrier (BBB). The scientific community is urgently seeking innovative and effective ...

Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment

Almajed, Zeyad Mohamed; AlSawaftah, Nour Majdi; Sulieman, Hana; Husseini, Ghaleb (American Scientific Publishers, 2023-07)

Ultrasound (US) has numerous uses in the medical field, including imaging, tumor ablation, and lithotripsy; another interesting application of US in cancer therapy is as an external trigger in targeted drug delivery. ...

Video-Based Recognition of Human Activity Using Novel Feature Extraction Techniques

Issa, Obada; Shanableh, Tamer (MDPI, 2023-06-05)

This paper proposes a novel approach to activity recognition where videos are compressed using video coding to generate feature vectors based on compression variables. We propose to eliminate the temporal domain of feature ...

Liposomes for the Treatment of Brain Cancer — A Review

Raju, Richu; Abuwatfa, Waad Hussein; Pitt, William G.; Husseini, Ghaleb (MDPI, 2023-06-25)

Due to their biocompatibility, non-toxicity, and surface-conjugation capabilities, liposomes are effective nanocarriers that can encapsulate chemotherapeutic drugs and facilitate targeted delivery across the blood–brain ...

A Review on Membrane Fouling Prediction Using Artificial Neural Networks (ANNs)

Abuwatfa, Waad Hussein; AlSawaftah, Nour Majdi; Darwish, Naif A.; Pitt, William G.; Husseini, Ghaleb (MDPI, 2023-07-24)

Membrane fouling is a major hurdle to effective pressure-driven membrane processes, such as microfiltration (MF), ultrafiltration (UF), nanofiltration (NF), and reverse osmosis (RO). Fouling refers to the accumulation of ...

Comparative Evaluation of Membrane Filtration on the Tertiary Treatment of Synthetic Secondary Effluent

Mortula, Maruf; Abdelrahman, Malak; Tatan, Bushra (MDPI, 2022-02)

Wastewater reuse is essential for sustainable water management. However, it requires tertiary treatment within the plant to ensure suitable water quality. This project aims to investigate the comparative performance of ...

Static Video Summarization Using Video Coding Features with Frame-level Temporal Sub-Sampling and Deep Learning

Issa, Obada; Shanableh, Tamer (MDPI, 2023)

There is an abundance of digital video content due to the cloud’s phenomenal growth and security footage, it is therefore essential to summarize these videos in data centers. This paper offers innovative approaches to the ...

Process simulation and analysis of a five-step copper–chlorine thermochemical water decomposition cycle for sustainable hydrogen production

Orhan, Mehmet Fatih; Dincer, Ibrahim; Rosen, Marc (Wiley, 2014)

A process model of a five-step copper–chlorine (Cu–Cl) cycle is developed and simulated with the Aspen Plus simulation code. Energy and mass balances, stream flows and properties, heat exchanger duties, and shaft work are ...

Numerical Analysis of Film Cooling Shield Formed by Confined Jet Discharging on a Flat Plate

Al-Hemyari, Mohammed; Hamdan, Mohammad; Orhan, Mehmet Fatih (International Information and Engineering Technology Association, 2019)

The effects of centrifugal force and thermal conductivity on the effectiveness of a film cooling shield are investigated in this study. A confined jet with 90 degree angle is used, to inject cooling fluid into hot steam, ...

Investigation of an integrated hydrogen production system based on nuclear and renewable energy sources: a new approach for sustainable hydrogen production via copper–chlorine thermochemical cycles

Orhan, Mehmet Fatih; Dincer, Ibrahim; Rosen, Marc (Wiley, 2011)

Hydrogen production via thermochemical water decomposition is a potential process for direct utilization of nuclear thermal energy to increase efficiency and thereby facilitate energy savings. Thermochemical water splitting ...

Design and simulation of a UOIT copper–chlorine cycle for hydrogen production

Orhan, Mehmet Fatih; Dincer, Ibrahim; Rosen, Marc (Wiley, 2012)

A design and simulation study of the four-step copper–chlorine (Cu–Cl) cycle using Aspen Plus software (Aspen Technology Inc., Cambridge, MA)is reported. The simulation consists of four main sections: hydrolysis, ...

Exergy analysis of heat exchangers in the copper–chlorine thermochemical cycle to enhance thermal effectiveness and cycle efficiency

Orhan, Mehmet Fatih; Dincer, Ibrahim; Rosen, Marc (Oxford University Press, 2011)

Most existing nuclear power plants in North America are typically water-cooled and operate at 250–500°C. For this temperature level, the copper–chlorine (Cu–Cl) cycle is one of the most promising cycles that can be integrated ...

Optimization of a Confined Jet Geometry to Improve Film Cooling Performance Using Response Surface Methodology (RSM)

Al-Hemyari, Mohammed; Hamdan, Mohammad; Orhan, Mehmet Fatih (MDPI, 2020)

This study investigates the interrelated parameters affecting heat transfer from a hot gas flowing on a flat plate while cool air is injected adjacent to the flat plate. The cool air forms an air blanket that shield the ...

Evaluating velocity and temperature fields for Ranque Hilsch vortex tube using numerical simulation

Al Saghir, Ahmad Mohammad; Hamdan, Mohammad; Orhan, Mehmet Fatih (Elsevier, 2021)

In this study, a three-dimensional numerical investigation is carried out to study the flow field inside a Ranque-Hilsch vortex tube (RHVT) model. Flow parameters such as velocity, temperature, and pressure are plotted at ...

Design and Comparison Analysis of Various Flow Configurations in Bipolar Plates via Numerical Simulation

Azzam, Mohammed H. A.; Qaq, Zabayyan; Orhan, Mehmet Fatih (Canadian Center of Science and Education, 2021)

Bipolar plates play a major role in the overall performance of fuel cells, hence their proper design and optimization are essential. In this regard, pressure drop across bipolar plates has a major impact on the efficiency. ...

Design and Optimization of Fuel Cells: A Case Study on Polymer Electrolyte Membrane Fuel Cell Power Systems for Portable Applications

Orhan, Mehmet Fatih; Saka, Kenan; Yousuf, Mohammad Hani (Wiley, 2022)

Fuel cells are energy conversion devices that directly convert chemical energy of fuels such as hydrogen to useful work with negligible environmental impact and high efficiency. This study deals with thermodynamic analysis ...