Browsing Department of Biology, Chemistry and Environmental Sciences by Author "9b0adb26-e9a6-4137-91d5-6e6a94b4e0b3"
Now showing items 1-8 of 8
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Analysis of macro and micro elemental composition of different extracts and finished products of the medicinal Herb – Terminalia bellirica
Gunasekar, Conjeevaram J.; Abu-Yousef, Imad; Narasimhan, Srinivasan; Majdalawieh, Amin (PKP, 2019)Terminalina bellirica is considered to be a sacred plant with five distinctive tastes (sweet, sour, salty, bitter, and pungent). It stimulates the proper functioning of the digestive system, sensory organs and it is very ... -
Anti-Bacterial and Anti-Fungal Activity of Xanthones Obtained via Semi-Synthetic Modification of α-Mangostin from Garcinia mangostana
Narasimhan, Srinivasan; Maheshwaran, Shanmugam; Abu-Yousef, Imad; Majdalawieh, Amin; Rethavathi, Janarthanam; Das, Prince Edwin; Poltronieri, Palmiro (MDPI, 2017)The microbial contamination in food packaging has been a major concern that has paved the way to search for novel, natural anti-microbial agents, such as modified α-mangostin. In the present study, twelve synthetic analogs ... -
Efficient and simple protocol employing borohydride systems to design a selective osthol-zirconium (OST-Zr) library from potential natural products
Viswanathan, Radhakrishnan; Abu-Yousef, Imad; Majdalawieh, Amin; Das, Prince Edwin; Narasimhan, Srinivasan (PKP, 2016)“Drug likeness” of a molecule is the prime criterion for a molecule to exhibit the desired pharmaceutical activity. A pharmacophore, which describes molecular features that are necessary for molecular recognition of a ... -
Evaluation of the interaction potential of synthetic ethylene glycol compounds with nuclear Factor κB
Narasimhan, Srinivasan; Majdalawieh, Amin; Abu-Yousef, Imad; Shanmugarajan, Dhivya; Ramasubramanian, Vishvanathan (PKP, 2013)In the last three decades, nuclear factor κB (NF-κB) has been the focus of many researchers who are interested in understanding the various molecular mechanisms involved in inflammatory diseases and cancer. Interference ... -
Green Synthesis of Encapsulated Copper Nanoparticles Using a Hydroalcoholic Extract of Moringa oleifera Leaves and Assessment of Their Antioxidant and Antimicrobial Activities
Das, Prince Edwin; Abu-Yousef, Imad; Majdalawieh, Amin; Narasimhan, Srinivasan; Poltronieri, Palmiro (MDPI, 2020)The synthesis of metal nanoparticles using plant extracts is a very promising method in green synthesis. The medicinal value of Moringa oleifera leaves and the antimicrobial activity of metallic copper were combined in the ... -
Immunomodulatory and Anti-Inflammatory Effects of Berberine in Lung Tissue and its Potential Application in Prophylaxis and Treatment of COVID-19
Majdalawieh, Amin; Yousef, Sarah M.; Abu-Yousef, Imad; Nasrallah, Gheyath K. (IMR Press, 2022)Natural products with known safety profiles are a promising source for the discovery of new drug leads. Berberine presents an example of one such phytochemical that has been extensively studied for its anti-inflammatory ... -
Potential immunomodulatory role of sesamin in combating immune dysregulation associated with COVID-19
Majdalawieh, Amin; Yousef, Sarah M.; Abu-Yousef, Imad (Medknow Publications, 2021)The ongoing outbreak of novel coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused an unprecedented global health crisis. Development of a cure for this ... -
Preparation and characterization of gatifloxacin-loaded sodium alginate hydrogel membranes supplemented with hydroxypropyl methylcellulose and hydroxypropyl cellulose polymers for wound dressing
Prabu, Durai; Majdalawieh, Amin; Abu-Yousef, Imad; Inbasekaran, Kadambari; Balasubramaniam, Tharani; Nallaperumal, Narayanan; Gunasekar, Conjeevaram J. (PKP, 2016)Introduction: The aim of this study is to evaluate gatifloxacin-loaded sodium alginate hydrogel membranes, supplemented with glycerol (a plasticizer), glutaraldehyde (a cross-linking agent), and hydroxypropyl methylcellulose ...