Browsing Masters Theses by Author "7c18f636-cd4c-41cc-975f-d05d56d982eb"
Now showing items 1-20 of 31
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Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment
Mohammad, Najla (2016-01)Chemotherapy is frequently used in cancer treatment. However, side effects associated with this type of treatment are often detrimental to the patient's health. This thesis discusses a novel approach of delivering a cytotoxic ... -
Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs) and Ultrasound.
Ibrahim, Mihad (2016-05)Cancer is defined as the uncontrolled growth of abnormal cells. Although billions of dollars have been spent on cancer research to develop its treatments, cancer still remains a major illness for mankind, partly due to the ... -
Autonomous Mobile Robots in Nature: Transfer RNAs in Escherichia coli Bacteria
Piros, Sandor (2008-05)Transfer RNAs (tRNAs) are the smallest autonomous robots on earth. They can recognize a specific amino acid from the possible pool of 20 different amino acids. They are able to transport these protein building blocks to ... -
DNA Base-Calling
Mohammed, Omniyah Gul (2010-05)The human genome sequence, consisting of approximately three billion bases, was decoded in the last decade as a result of the Human Genome Project. Information derived from the genomic sequences of different species is ... -
DNA Base-Calling Techniques
Odeh, Fadi (2008-12)The availability of substantial amounts of DNA sequence information has begun to revolutionize the practice of biology. So it is obvious that manual sequencing output is not adequate to keep pace with the growing demand ... -
Doxorubicin-encapsulated Albumin liposomes with acoustic triggering for cancer treatment
Farooq, Afifa (2019-05)With cancer being the leading cause of death worldwide, increasing economic and social resources are being directed by researchers and healthcare professionals to treat the disease, or at least provide palliative care to ... -
Dynamics of Chemotherapeutic Drug Release from Liposomes Using Low-Frequency Ultrasound
Ahmed, Salma Elgaili (2015-01)This thesis focuses on the study of liposomes; nanoparticles that can act as anticancer drug carriers, in combination with ultrasound applied as a drug trigger, with the objective of reducing the side effects caused by ... -
The Effect of Ultrasound on the Drug Delivery of RGD-Targeted Liposomes
Mahmoud, Mohamad (2018-05)Approaches used to treat cancer, with the most prominent being chemotherapy, have detrimental effects on patients’ health. Doxorubicin, a chemotherapeutic agent, alters normal cellular functions and can cause many fatal ... -
The Effects of cRGD Targeting Liposomes When Paired With Ultrasonic Waves on Drug Delivery
Kosaji, Doua Jamal (2021-04)Cancer is a leading fatal disease, which has the ability to grow uncontrollably and spread throughout the body of the patient. Several approaches have been used to treat cancer, chemotherapy being the most common treatment ... -
Encapsulation and Release of Calcein from Herceptin-conjugated eLiposomes
Zafar, Mah Noor (2023-06) -
Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy
Al Bostami, Rouba D. (2023-11)Breast cancer, the predominant and frequently recurring cancer in women on a global scale, presents challenges to traditional chemotherapy methods. This is primarily due to issues such as systemic toxicity, low solubility, ... -
Folated Liposomes and Ultrasound to Induce the Controlled Release of a Model Drug
Ba-Hutair, Wafa Nasser Mohammed (2023-04) -
Functionalized Metal Organic Frameworks For Chemotherapy Drug Delivery
Ahmed, Ahmed H.S (2020-11)Cancer is the leading cause of death worldwide, and can be treated by various methods or sometimes a combination of different treatments. Chemotherapy is one of the conventional methods of treatment. Although it is effective ... -
In Vitro Cell Work of Two Types of Targeted Nanoparticles with Ultrasound Triggering
Abuwatfa, Waad Hussein (2020-11)Targeted liposomes have shown promising potential as effective chemotherapeutics delivery vehicles in Smart Drug Delivery Systems (SDDSs). Upon accumulation and internalization at the tumor site, the liposomes need to be ... -
Investigating and Modeling the Acoustic Release of Doxorubicin from Folate Targeted Micelles
Kherbeck, Laura (2012-06)To minimize the adverse side effects of conventional chemotherapy, a targeted micellar drug carrier was investigated that retains hydrophobic drugs in its core and then releases the drug via ultrasound. This thesis reports ... -
Investigation and Mathematical Modeling of Acoustic Release of Doxorubicin from Micelles
Alhariri, Youssef Ashraf (2020-05)Given the growing concern over the increasing number of people diagnosed with cancer and the high prevalence of unwanted side effects associated with chemotherapy on healthy tissues, this thesis aims to provide better, ... -
Liposomal drug release using ultrasound and modeling release dynamics for model predictive controller design
Moussa, Hesham Gamal (2015-06)Chemotherapy is widely used for cancer treatment; however, it causes unwanted side effects in patients such as fatigue, weight loss, pain, hair fall and nausea. Those side effects are due to the fact that most of the ... -
Lipsome-coated metal organic frameworks as a new drug nanocarrier
Mohamed, Omnia A. (2019-12)Cancer has emerged to become one of the predominant diseases ever known to humanity, with chemotherapeutic agents as leading methods for treating it. However, this blind-sighted treatment method that targets all cells; ... -
Modeling of In vitro Release Kinetics of Ultrasound-triggered Targeted Liposomes
Almajed, Zeyad Mohamed (2022-04)Ultrasound-triggered, targeted liposomes are a promising drug delivery system as they potentially improve the clinical outcomes of chemotherapy while reducing associated side effects. However, the common drug release models ... -
A Novel Cancer Treatment Platform Utilizing HER2-Immunoliposomes and Ultrasound
Ajith, Saniha Aysha (2020-05)Cancer is defined as the uncontrolled growth of cells in the body. It is one of the leading causes of death worldwide. One of the most common approaches to destroy cancer cells is via chemotherapy treatment, in which ...