Department of Chemical and Biological Engineering
Work by the faculty and students of the Department of Chemical Engineering
Recent Submissions
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Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
(MDPI, 2023)Cancer is one of the leading causes of death worldwide. Because each person’s cancer may be unique, diagnosing and treating cancer is challenging. Advances in nanomedicine have made it possible to detect tumors and quickly ... -
Transferrin-Targeted Liposomes in Glioblastoma Therapy: A Review
(MDPI, 2026-08-26)Glioblastoma (GBM) is a highly aggressive brain tumor, and its treatment is further complicated by the high selectivity of the blood–brain barrier (BBB). The scientific community is urgently seeking innovative and effective ... -
Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment
(American Scientific Publishers, 2023-07)Ultrasound (US) has numerous uses in the medical field, including imaging, tumor ablation, and lithotripsy; another interesting application of US in cancer therapy is as an external trigger in targeted drug delivery. ... -
Liposomes for the Treatment of Brain Cancer — A Review
(MDPI, 2023-06-25)Due to their biocompatibility, non-toxicity, and surface-conjugation capabilities, liposomes are effective nanocarriers that can encapsulate chemotherapeutic drugs and facilitate targeted delivery across the blood–brain ... -
A Review on Membrane Fouling Prediction Using Artificial Neural Networks (ANNs)
(MDPI, 2023-07-24)Membrane fouling is a major hurdle to effective pressure-driven membrane processes, such as microfiltration (MF), ultrafiltration (UF), nanofiltration (NF), and reverse osmosis (RO). Fouling refers to the accumulation of ... -
Enhancement of the corrosion resistance of mild steel with femtosecond laser- nanostructuring and CrCoNi medium entropy alloy coating
(Elsevier, 2022)In this work, the corrosion resistance of mild steel surface nanostructured with a femtosecond laser and coated with high corrosion resistant CrCoNi (CCN) medium entropy alloy through magnetron sputtering is studied. ... -
Tumor vasculature vs tumor cell targeting: Understanding the latest trends in using functional nanoparticles for cancer treatment
(Elsevier, 2023)Delivering drugs to tumors using nanoparticles (NPs) has shown promising potential in promoting targeted drug delivery of antineoplastic agents to enhance their efficiency while reducing the associated systemic toxicity. ... -
A Comparative Analysis of Numerical Methods for Solving the Leaky Fire and Integrate Model
(MDPI, 2023)The human nervous system is one of the most complex systems of the human body. Understanding its behavior is crucial in drug discovery and developing medical devices. One approach to understanding such a system is to model ... -
Acoustically-Activated Liposomal Nanocarriers to Mitigate the Side Effects of Conventional Chemotherapy with a Focus on Emulsion-Liposomes
(MDPI, 2023)To improve currently available cancer treatments, nanomaterials are employed as smart drug delivery vehicles that can be engineered to locally target cancer cells and respond to stimuli. Nanocarriers can entrap chemotherapeutic ... -
Comprehensive Study of a Diabetes Mellitus Mathematical Model Using Numerical Methods with Stability and Parametric Analysis
(MDPI, 2023-01-04)Diabetes is sweeping the world as a silent epidemic, posing a growing threat to public health. Modeling diabetes is an effective method to monitor the increasing prevalence of diabetes and develop cost-effective strategies ... -
A Review on Membrane Biofouling: Prediction, Characterization, and Mitigation
(MDPI, 2022-12-15)Water scarcity is an increasing problem on every continent, which instigated the search for novel ways to provide clean water suitable for human use; one such way is desalination. Desalination refers to the process of ... -
Modeling of the In Vitro Release Kinetics of Sonosensitive Targeted Liposomes
(MDPI, 2022-12-05)Targeted liposomes triggered by ultrasound are a promising drug delivery system as they potentially improve the clinical outcomes of chemotherapy while reducing associated side effects. In this work, a comprehensive model ... -
In Vitro Evaluation of Ultrasound Effectiveness in Controlling Doxorubicin Release from Albumin-Conjugated Liposomes
(American Scientific Publishers, 2022)Functionalized liposomes are among the most promising antineoplastic agents delivery vehicles. Contemporaneous to their accretion at the tumor site, they need to be potentiated to release their cargo using a suitable ... -
Novel algorithms for accurate DNA base-calling
(Scientific Research Publishing, 2013)The ability to decipher the genetic code of different species would lead to significant future scientific achievements in important areas, including medicine and agriculture. The importance of DNA sequencing necessitated ... -
Gold-Nanoparticle Hybrid Nanostructures for Multimodal Cancer Therapy
(MDPI, 2022)With the urgent need for bio-nanomaterials to improve the currently available cancer treatments, gold nanoparticle (GNP) hybrid nanostructures are rapidly rising as promising multimodal candidates for cancer therapy. Gold ... -
The Kinetics of Calcein Release from Mixed Targeted Liposomes Using Ultrasound
(American Scientific Publishers, 2022)Site-specific delivery of chemotherapeutics using actively targeted-stimuli-responsive liposomes is a promising approach to enhance the therapeutic efficiency of anti-cancer drugs while reducing the associated undesirable ... -
Effect of High-Frequency Ultrasound on Targeted Liposomes
(American Scientific Publishers, 2022)Delivering highly toxic drugs inside a safe carrier to tumors while achieving a controlled and effective drug release at the targeted sites represents an attractive approach to enhance drug efficiency while reducing its ... -
Combined and Single Doxorubicin/Naproxen Drug Loading and Dual-Responsive pH/Ultrasound Release from Flexible Metal-Organic Framework Nanocarriers
(American Scientific Publishers, 2022)In this study, the flexible aluminum-based MIL-53(Al) metal-organic framework was loaded with doxorubicin (DOX) and naproxen (NAP) and was examined as a promising pH/ultrasound dual-responsive drug delivery system. The two ... -
Redox-Responsive Drug Delivery Systems: A Chemical Perspective
(MDPI, 2022)With the widespread global impact of cancer on humans and the extensive side effects associated with current cancer treatments, a novel, effective, and safe treatment is needed. Redoxresponsive drug delivery systems (DDSs) ... -
Ultrasound Triggering of Liposomal Nanodrugs for Cancer Therapy: A Review
(MDPI, 2022)Efficient conventional chemotherapy is limited by its nonspecific nature, which causes severe systemic toxicity that can lead to patient discomfort and low therapeutic efficacy. The emergence of smart drug delivery systems ...
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