Now showing items 1-6 of 6

    • The effect of pegylation and targeting moieties on the ultrasound-mediated drug release from liposomes 

      Awad, Nahid S.; Paul, Vinod; Mahmoud, Mohamad; AlSawaftah, Nour Majdi; Kawak, Paul S.; Al-Sayah, Mohammad; Husseini, Ghaleb (ACS Publications, 2019)
      The use of targeted liposomes encapsulating chemotherapy drugs enhances the specific targeting of cancer cells, thus, reducing the side effects of these agents and providing a more patient-friendly treatment. Targeted ...
    • Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release 

      Ahmed, Salma E.; Awad, Nahid S.; Paul, Vinod; Moussa, Hesham Gamal; Husseini, Ghaleb (Bentham Science Publishers, 2018)
      Conventional chemotherapeutics lack the specificity and controllability, thus may poison healthy cells while attempting to kill cancerous ones. Newly developed nano-drug delivery systems have shown promise in delivering ...
    • Multi-Model Investigation and Adaptive Estimation of the Acoustic Release of a Model Drug From Liposomes 

      Wadi, Ali; Abdel-Hafez, Mamoun; Husseini, Ghaleb; Paul, Vinod (IEEE, 2019)
      This paper researches a suitable mathematical model that can reliably predict the release of a model drug (namely calcein) from biologically targeted liposomal nanocarriers triggered by ultrasound. Using mathematical models, ...
    • Targeting Breast Cancer Using Hyaluronic Acid-Conjugated Liposomes Triggered with Ultrasound 

      Ben-Daya, Mohamed; Paul, Vinod; Awad, Nahid S.; AlSawaftah, Nour Majdi; Al-Sayah, Mohammad; Husseini, Ghaleb (American Science Publishers, 2021)
      The successful targeting of tumors can be achieved by conjugating targeting moieties to nanoparticles. These modifications allow nannocarriers to achieve greater targeting specificity through binding to specific receptors ...
    • Ultrasonically Controlled Albumin-conjugated Liposomes for Breast Cancer Therapy 

      Awad, Nahid S.; Paul, Vinod; Al-Sayah, Mohammad; Husseini, Ghaleb (Taylor and Francis Online, 2019)
      Targeted liposomes have high potentials in the specific and effective delivery of their loaded therapeutic agents to the tumor site. Once at the tumor site, it is important that these liposomes are triggered to release ...
    • Ultrasound‑triggered herceptin liposomes for breast cancer therapy 

      Elamir, Amal; Aysha Ajith, Saniha; AlSawaftah, Nour Majdi; Abuwatfa, Waad Hussein; Mukhopadhyay, Debasmita; Paul, Vinod; Al-Sayah, Mohammad; Awad, Nahid S.; Husseini, Ghaleb (Nature, 2021)
      The functionalization of liposomes with monoclonal antibodies is a potential strategy to increase the specificity of liposomes and reduce the side-effects associated with chemotherapeutic agents. The active targeting of ...