Now showing items 1-2 of 2

    • Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery 

      Staples, Bryant J.; Pitt, William G.; Roeder, Beverly L.; Husseini, Ghaleb; Rajeev, Deepthi; Schaalje, G. Bruce (Elsevier, 2010)
      Ultrasound (US) increases efficacy of drugs delivered from micelles, but the pharmacokinetics have not been studied previously. In this study, US was used to deliver doxorubicin (Dox) sequestered in micelles in an in vivo ...
    • Role of frequency and mechanical index in ultrasonic-enhanced chemotherapy in rats 

      Staples, Bryant J.; Roeder, Beverly L.; Husseini, Ghaleb; Badamjav, Odgerel; Schaalje, G. Bruce; Pitt, William G. (Springer, 2009)
      Purpose The therapeutic effect of ultrasound and micellar-encapsulated doxorubicin was studied in vivo using a tumor-bearing rat model with emphasis on how tumor growth rate is affected by ultrasonic parameters such as ...