Browsing Department of Chemical and Biological Engineering by Title
Now showing items 110-129 of 191
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Multi-Model Investigation and Adaptive Estimation of the Acoustic Release of a Model Drug From Liposomes
(IEEE, 2019)This paper researches a suitable mathematical model that can reliably predict the release of a model drug (namely calcein) from biologically targeted liposomal nanocarriers triggered by ultrasound. Using mathematical models, ... -
Multifunctional Nanovehicles for Combined 5-Fluorouracil and Gold Nanoparticles Based on the Nanoprecipitation Method
(American Scientific Publishers, 2011)To facilitate the administration of combined 5-Fluorouracil (5-FU) and gold nanoparticles (for photothermal treatment purposes), we developed 5-FU-gold-poly(lactide-co-glycolic acid) (5-FU-Au- PLGA) nanovehicles, via the ... -
Nanoparticle-based materials in anticancer drug delivery: Current and future prospects
(Elsevier, 2023)The past decade has witnessed a breakthrough in novel strategies to treat cancer. One of the most common cancer treatment modalities is chemotherapy which involves administering anti-cancer drugs to the body. However, these ... -
Non-Viral Gene Transfection with Ultrasound: Is 100% Transfection Possible?
(American Scientific Publishers, 2012)Ultrasound has been used as a modality to enhance the transfection of cells, purportedly via entry of genetic material through defects in the cell membrane produced by bubble cavitation events. A mathematical model was ... -
Novel algorithms for accurate DNA base-calling
(Scientific Research Publishing, 2013)The ability to decipher the genetic code of different species would lead to significant future scientific achievements in important areas, including medicine and agriculture. The importance of DNA sequencing necessitated ... -
Optimizing the use of ultrasound to deliver chemotherapeutic agents to cancer cells from polymeric micelles
(Elsevier, 2011)In this study, we present an artificial neural network (ANN) model that attempts to predict the dynamic release of doxorubicin (Dox) from P105 micelles under different ultrasonic power densities at 20 kHz. The goal is to ... -
Optimum ethane recovery in conventional turboexpander process
(Elsevier, 2010)Ethane recovery in a conventional turboexpander process is optimized considering different demethanizer pressures and different feeds: a lean gas and a rich one. The design variables are varied, while meeting process ... -
Over-Pressure Suppresses Ultrasonic-Induced Drug Uptake
(Elseviser, 2008)Ultrasound (US) is used to enhance and target delivery of drugs and genes to cancer tissues. The present study further examines the role of acoustic cavitation in US-induced permeabilization of cell membranes and subsequent ... -
Parametric Study of a Single Effect Lithium Bromide-Water Absorption Chiller Powered by a Renewable Heat Source
(SDEWES, 2020)This work investigates the performance of a single-effect absorption chiller utilizing an aqueous lithium bromide solution as the working fluid and driven by hot fluid rejected from either a geothermal power plant or the ... -
pH and ultrasound dual-responsive drug delivery system based on PEG–folate-functionalized Iron-based metal–organic framework for targeted doxorubicin delivery
(Elsevier, 2021)In recent years, the use of metal–organic frameworks (MOFs) as drug nanocarriers has gained attention because of their extraordinary physical and chemical properties. In this work, dual-responsive iron-based MOFs were ... -
pH-Responsive Nanocarriers in Cancer Therapy
(MDPI, 2022)A number of promising nano-sized particles (nanoparticles) have been developed to conquer the limitations of conventional chemotherapy. One of the most promising methods is stimuli-responsive nanoparticles because they ... -
Phase transitions of nanoemulsions using ultrasound: Experimental observations
(Elsevier, 2012)The ultrasound-induced transformation of perfluorocarbon liquids to gases is of interest in the area of drug and gene delivery. In this study, three independent parameters (temperature, size, and perfluorocarbon species) ... -
Phase transitions of perfluorocarbon nanoemulsion induced with ultrasound: A mathematical model
(Elsevier, 2013)While ultrasound has been used in many medical and industrial applications, only recently has research been done on phase transformations induced by ultrasound. This paper presents a numerical model and the predicted results ... -
Photo-Induced Drug Release from Polymeric Micelles and Liposomes: Phototriggering Mechanisms in Drug-Delivery Systems
(MDPI, 2022)Chemotherapeutic drugs are highly effective in treating cancer. However, the side effects associated with this treatment lower the quality of life of cancer patients. Smart nanocarriers are able to encapsulate these drugs ... -
Photocatalytic demulsification of oil/water emulsions containing nonionic surfactant
(Springer, 2020-11)Separation of oil-water (OW) emulsions is investigated using a photocatalytic demulsification approach. Experiments were conducted using two types of photocatalysts, namely, ZnO and TiO2. The emulsion samples were prepared ... -
Photochemical Lithography: Creation of Patterned, Acid Chloride Functionalized Surfaces Using UV Light and Gas-Phase Oxalyl Chloride
(American Chemical Society, 2003) -
Possible Physical Mechanisms of tRNA Pre-Selection in the Cytoplasm of Escherichia coli Bacteria
(American Scientific Publishers, 2010)In a previous publication, we used kinetic models to simulate the physical movement ofthe transfer RNA (tRNA) in the cytoplasm of Escherichia coli and concluded that tRNA molecules are not able to approach the ribosome by ... -
Predicting the Release of Chemotherapeutics From the Core of Polymeric Micelles Using Ultrasound
(IEEE Explore, 2015)In this paper, the estimation of acoustic drug release from micelles is addressed. The release is measured as a decrease in fluorescence once ultrasound is applied. Initially, a Kalman filter is used to fuse the drug ... -
Preliminary Modeling of Transfer RNA Kinetics in the Cytoplasm of Escherichia coli Bacteria
(American Scientific Publishers, 2010)Transfer RNAs (tRNAs) can recognize a specific amino acid from a possible pool of 20. Theyare able to transport these protein building-blocks to the ribosome, the site where amino acids assemble into protein chains. Accurate ... -
Preliminary Results of Combining Low Frequency Low Intensity Ultrasound and Liposomal Drug Delivery to Treat Tumors in Rats
(American Scientific Publishers, 2011)Ultrasound is a convenient trigger for site-specific drug delivery in cancer therapy. Nanosized liposomes formulated from soy phosphatidyl choline, cholesterol, 1,2-distearoyl-sn-glycero- 3-phosphoethanolamine-N-[carboxy ...