Browsing Department of Chemical and Biological Engineering by Subject "Doxorubicin"
Now showing items 21-26 of 26
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Release of Doxorubicin from Unstabilized and Stabilized Micelles Under the Action of Ultrasound
(American Scientific Publishers, 2007)Polymeric micelles are being investigated as chemotherapy drug delivery carriers using ultrasound as a trigger mechanism. The aim of this paper is to measure the release of Doxorubicin (Dox) from the core of unstabilized ... -
The role of cavitation in acoustically activated drug delivery
(Elsevier Science Direct, 2005)Pluronic P105 micelles are potential candidates as chemotherapy drug delivery vehicles using ultrasonic stimulation as a release trigger. Acoustic power has been previously shown to release two anthracycline agents from ... -
Targeting the Folate Receptor: Effects of Conjugating Folic Acid to DOX Loaded Polymeric Micelles
(Bentham Science Publishers, 2016)In this paper, we report on a potential cancer drug delivery system that utilizes the ligand targeting of the folate receptor. Our drug delivery system consists of Pluronic-P105 micelles, targeted with folic acid moieties. ... -
Ultrasonic release of doxorubicin from Pluronic P105 micelles stabilized with an interpenetrating network of N,N diethylacrylamide
(Elsevier, 2002)Pluronic P105 micelles sequester hydrophobic drugs and release them upon insonation with low frequency ultrasound; however these micelles dissolve relatively quickly upon dilution. The objective of this research was to ... -
The use of ultrasound to release chemotherapeutic drugs from micelles and liposomes
(Taylor & Francis, 2014)Several drug delivery systems have been investigated to reduce the side effects of chemotherapy by encapsulating the therapeutic agent in a nanosized carrier until it reaches the tumor site. Many of these particles are ... -
Using Artificial Neural Networks and Model Predictive Control to Optimize Acoustically Assisted Doxorubicin Release from Polymeric Micelles
(SAGE Publications, 2009)We have been developing a drug delivery system that uses Pluronic P105 micelles to sequester a chemotherapeutic drug - namely, Doxorubicin (Dox) - until it reaches the cancer site. Ultrasound is then applied to release the ...