Browsing Department of Chemical and Biological Engineering by Title
Now showing items 159-178 of 189
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Targeting Breast Cancer Using Hyaluronic Acid-Conjugated Liposomes Triggered with Ultrasound
(American Science Publishers, 2021)The successful targeting of tumors can be achieved by conjugating targeting moieties to nanoparticles. These modifications allow nannocarriers to achieve greater targeting specificity through binding to specific receptors ... -
Targeting the Folate Receptor: Effects of Conjugating Folic Acid to DOX Loaded Polymeric Micelles
(Bentham Science Publishers, 2016)In this paper, we report on a potential cancer drug delivery system that utilizes the ligand targeting of the folate receptor. Our drug delivery system consists of Pluronic-P105 micelles, targeted with folic acid moieties. ... -
Technique for Drug and Gene Delivery to the Cell Cytosol
(2015-04-07)Provided herein is a composition, a method, and a system for delivering a functional molecule to the cytosol of a cell, comprising a liposome configured to be taken into a cell, including by a process selected from the ... -
Thermal Conductivities of Choline Chloride-Based Deep Eutectic Solvents and Their Mixtures with Water: Measurement and Estimation
(MDPI, 2020)The thermal conductivities of selected deep eutectic solvents (DESs) were determined using the modified transient plane source (MTPS) method over the temperature range from 295 K to 363 K at atmospheric pressure. The results ... -
Thermal Conductivities of Choline Chloride-Based Deep Eutectic Solvents and Their Mixtures with Water: Measurement and Estimation
(MDPI, 2020)The thermal conductivities of selected deep eutectic solvents (DESs) were determined using the modified transient plane source (MTPS) method over the temperature range from 295 K to 363 K at atmospheric pressure. The results ... -
Thermosensitive Polymers and Thermo-Responsive Liposomal Drug Delivery Systems
(MDPI, 2022)Temperature excursions within a biological milieu can be effectively used to induce drug release from thermosensitive drug-encapsulating nanoparticles. Oncological hyperthermia is of particular interest, as it is proven ... -
Toxicological impact of nanoparticles on human health: A review
(American Scientific Publishers, 2022)Nanotechnology is a rapidly growing industry where nanomaterials are used in almost every field, including electronics, cosmetics, engineering, household products, biotechnology and medicine. Nanoparticles (NPs) have unique ... -
Transferrin-Targeted Liposomes in Glioblastoma Therapy: A Review
(MDPI, 2026-08-26)Glioblastoma (GBM) is a highly aggressive brain tumor, and its treatment is further complicated by the high selectivity of the blood–brain barrier (BBB). The scientific community is urgently seeking innovative and effective ... -
Transferrin‑modifed liposomes triggered with ultrasound to treat HeLa cells
(Nature, 2021)Targeted liposomes are designed to target specific receptors overexpressed on the surfaces of cancer cells. This technique ensures site-specific drug delivery to reduce undesirable side effects while enhancing the efficiency ... -
Tumor vasculature vs tumor cell targeting: Understanding the latest trends in using functional nanoparticles for cancer treatment
(Elsevier, 2023)Delivering drugs to tumors using nanoparticles (NPs) has shown promising potential in promoting targeted drug delivery of antineoplastic agents to enhance their efficiency while reducing the associated systemic toxicity. ... -
Ultrasonic Drug Delivery Using Micelles and Liposomes
(Springer, 2016)The encapsulation of drugs in nanocarriers revolutionized research in drug delivery, especially in cancer chemotherapeutics. Several nanosystems have been developed including liposomes, polymeric micelles, dendrimers, solid ... -
Ultrasonic release of doxorubicin from Pluronic P105 micelles stabilized with an interpenetrating network of N,N diethylacrylamide
(Elsevier, 2002)Pluronic P105 micelles sequester hydrophobic drugs and release them upon insonation with low frequency ultrasound; however these micelles dissolve relatively quickly upon dilution. The objective of this research was to ... -
Ultrasonic-Activated Micellar Drug Delivery for Cancer Treatment
(Wiley InterSciences, 2008)The use of nanoparticles and ultrasound in medicine continues to evolve. Great strides have been made in the areas of producing micelles, nanoemulsions, and solid nanoparticles that can be used in drug delivery. An effective ... -
Ultrasonically Controlled Albumin-conjugated Liposomes for Breast Cancer Therapy
(Taylor and Francis Online, 2019)Targeted liposomes have high potentials in the specific and effective delivery of their loaded therapeutic agents to the tumor site. Once at the tumor site, it is important that these liposomes are triggered to release ... -
Ultrasonically triggered drug delivery: Breaking the barrier
(Elsevier, 2014)The adverse side-effects of chemotherapy can be minimized by delivering the therapeutics in time and space to only the desired target site. Ultrasound offers one fairly non-invasive method of accomplishing such precise ... -
Ultrasound in drug and gene delivery
(Elsevier, 2008)In this issue, we present the current applications and future prospects of ultrasound in various aspects of drug and gene delivery. There are many advantages to ultrasound that make it ideal for the delivery of therapeutics ... -
Ultrasound Triggering of Liposomal Nanodrugs for Cancer Therapy: A Review
(MDPI, 2022)Efficient conventional chemotherapy is limited by its nonspecific nature, which causes severe systemic toxicity that can lead to patient discomfort and low therapeutic efficacy. The emergence of smart drug delivery systems ... -
Ultrasound-Induced Calcein Release From eLiposomes
(Elsevier, 2012)Ultrasound is explored as a method of inducing the release of encapsulated materials from eLiposomes, defined as liposomes containing emulsion droplets. Emulsions were formed using perfluorohexane and perfluoropentane. ... -
Ultrasound-induced doxorubicin release from folate-targeted and non-targeted P105 micelles: a modeling study
(De Gruyter, 2016)The aim of this work is to study the kinetics of ultrasound (70 kHz) – using a kinetic model that takes into account cavitation events and drug re-encapsulation upon the cessation of the acoustic field. The simulation ... -
Ultrasound-Mediated Cancer Therapeutics Delivery using Micelles and Liposomes: A Review
(Bentham Science Publisher, 2021)Nanoparticles have proven promising as cancer theranostic tools. Nanoparticles are selective in nature, have reduced toxicity, and controllable drug release patterns making them ideal carriers for anticancer drugs. Numerous ...