Browsing Department of Chemical and Biological Engineering by Title
Now showing items 88-107 of 189
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Kinetics of Ultrasonic Drug Delivery from Targeted Micelles
(American Scientific Publishers, 2015)To minimize the adverse side effects of conventional chemotherapy, a targeted micellar drug carrier was investigated that retains hydrophobic drugs in its core and then releases the drug via ultrasonic activation. This ... -
Kinetics of ultrasonic release of doxorubicin from pluronic P105 micelles
(Elsevier, 2001)The aim of this research was to measure and model the kinetics of acoustic release and subsequent re-encapsulation of Doxorubicin (DOX) from Pluronic P105 micelles. A fluorescence detection ultrasound exposure chamber was ... -
Lessons learned from the underrepresentation of women in STEM: AI-enabled solutions and more
(Elsevier, 2021)The absence of women in STEM and energy sectors is driven by discrimination and socio-cultural factors. A greater number of women “leak out” from Energy and STEM fields than men. AI-enabled solutions offer analysis tools ... -
Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment
(American Scientific Publishers, 2023-07)Ultrasound (US) has numerous uses in the medical field, including imaging, tumor ablation, and lithotripsy; another interesting application of US in cancer therapy is as an external trigger in targeted drug delivery. ... -
Liposomes as a Promising Ultrasound-Triggered Drug Delivery System in Cancer Treatment
(Bentham Science, 2017)The initial uses of ultrasound waves in the medical field were limited to the thermal ablation of solid tumors and as a diagnostic tool. Recent advances at the preclinical stage have allowed the use of ultrasound as a ... -
Liposomes for the Treatment of Brain Cancer — A Review
(MDPI, 2023-06-25)Due to their biocompatibility, non-toxicity, and surface-conjugation capabilities, liposomes are effective nanocarriers that can encapsulate chemotherapeutic drugs and facilitate targeted delivery across the blood–brain ... -
Liposomes in Active, Passive and Acoustically-Triggered Drug Delivery
(Bentham Science Publishers, 2019)Cancer has become one of the most deadly noncommunicable diseases globally. Several modalities used to treat cancer patients exist today yet many have failed to prove high efficacy with low side effects. The most common ... -
Mapping of Embedded Functionalized Carbon Nanotubes in Poly(vinyl alcohol)/Nanotube Composite Using Electrostatic Force Microscopy
(Taylor & Francis, 2012)In the present study, electrostatic force microscopy (EFM) was used as a nondestructive tool for mapping individual functionalized single-wall carbon nanotubes (SWCNTs) incorporated in a poly(vinyl alcohol) (PVA)/CNT ... -
Mathematical modeling of microbubble cavitation at 70 kHz and the importance of the subharmonic in drug delivery from micelles
(Elsevier, 2013)In order to gain insight into the experimental observation of ultrasound-induced release of drugs from micelles, we modeled the dynamic oscillations of a 10-μm-diameter bubble insonated at 70 kHz. The Parlitz modification ... -
Measuring the Acoustic Release of a Chemotherapeutic Agent from Folate-Targeted Polymeric Micelles
(American Scientific Publishers, 2018)In this paper, we compare the use of Bayesian filters for the estimation of release and reencapsulation rates of a chemotherapeutic agent (namely Doxorubicin) from nanocarriers in an acoustically activated drug release ... -
Membrane bioreactor for wastewater treatment: A review
(Elsevier, 2021)Due to the growth in the human population globally, it is noted that various industries have also grown. The need for an excess supply of water and the generation of high effluent quality upon proper treatment technologies ... -
Micelles and nanoparticles for ultrasonic drug and gene delivery
(Elsevier, 2008)Drug delivery research employing micelles and nanoparticles has expanded in recent years. Of particular interest is the use of these nanovehicles that deliver high concentrations of cytotoxic drugs to diseased tissues ... -
Microbial Desalination Cell (MDC) in the Presence of Activated Carbon
(American Scientific Publishers, 2014-10)This report studies the performance of a Microbial Desalination Cell (MDC) in the presence ofactivated carbon in both the cathode and anode chambers. The large surface area of the activatedcarbon provides surface for ... -
Microbial Desalination Cells Technology: A Review and a Case Study
(Elsevier, 2015-03)The microbial desalination cell (MDC) is a newly-developed technology which integrates the microbial fuel cell (MFC) process and electrodialysis for wastewater treatment, water desalination and production of renewable ... -
Modeling and Bias-Robust Estimation of the Acoustic Release of Chemotherapeutics from Liposomes
(American Scientific Publishers, 2019)This paper models the acoustic drug release of chemotherapeutics from liposomes using a kinetic model that accounts for systematic biases affecting the drug delivery process. An optimal stochastic filter is then proposed ... -
Modeling and Sensitivity Analysis of Acoustic Release of Doxorubicin from Unstabilized Pluronic P105 Using an Artificial Neural Network Model
(Adenine Press, 2007)This paper models steady state acoustic release of Doxorubicin (Dox) from Pluronic P105 micelles using Artificial Neural Networks (ANN). Previously collected release data were compiled and used to train, validate, and test ... -
Modeling of Anti-cancer Drug Release Kinetics from Liposomes and Micelles: A review
(Institute of Electrical and Electronics Engineers, 2021)Nanocarriers, such as liposomes and micelles, were developed to enhance the delivery of therapeutic drugs to malignant tissues. Internal or external stimuli can be applied to achieve spatiotemporal controlled release from ... -
Modeling of Drug Release Kinetics from Stimuli- Responsive Micelles and Liposomes: A review
(IEEE, 2021)Nanocarriers such as micelles and liposomes were developed to enhance the delivery of therapeutic drugs to tumors. Internal or external stimuli can be applied to achieve spatiotemporal controlled release from these carriers. ... -
Modeling of the In Vitro Release Kinetics of Sonosensitive Targeted Liposomes
(MDPI, 2022-12-05)Targeted liposomes triggered by ultrasound are a promising drug delivery system as they potentially improve the clinical outcomes of chemotherapy while reducing associated side effects. In this work, a comprehensive model ... -
Modeling the Effects of Chemotherapy and Immunotherapy on Tumor Growth
(American Scientific Publishers, 2021)Mathematical modeling has been used to simulate the interaction of chemotherapy and immunotherapy drugs intervention with the dynamics of tumor cells growth. This work studies the interaction of cells in the immune system, ...