Browsing Department of Chemical and Biological Engineering by Title
Now showing items 36-55 of 189
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Degradation kinetics of stabilized Pluronic micelles under the action of ultrasound
(Elsevier, 2009)The majority of research in the area of acoustically-activated drug delivery from stabilized micelles has been focused on the rapid release of chemotherapy drugs from the core of such nano-carriers. Previous publications ... -
Development and Characterization of Novel Composite and Flexible Electrode Based on Titanium Dioxide
(IEEE, 2020-06-11)Flexible implantable bioelectrodes have the potential to advance neural sensing and muscle stimulation, especially in peripheral nerve injuries. In such cases, the application of electrical stimulation to muscles prevents ... -
Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery
(Elsevier, 2010)Ultrasound (US) increases efficacy of drugs delivered from micelles, but the pharmacokinetics have not been studied previously. In this study, US was used to deliver doxorubicin (Dox) sequestered in micelles in an in vivo ... -
DNA damage induced by micellar-delivered doxorubicin and ultrasound: comet assay study
(Elsevier, 2000)To minimize adverse side effects of chemotherapy, we have developed a micellar drug carrier that retains hydrophobic drugs, and then releases the drug by ultrasonic stimulation. This study investigated the DNA damage induced ... -
Drug delivery in pluronic micelles: effect of high-frequency ultrasound on drug release from micelles and intracellular uptake
(Elsevier, 2002)The effect of high-frequency ultrasound on doxorubicin (DOX) release from Pluronic micelles and intracellular DOX uptake was studied for promyelocytic leukemia HL-60 cells, ovarian carcinoma drug-sensitive and multidrug-resistant ... -
Drug Delivery Systems Based on Polymeric Micelles and Ultrasound: A Review
(Bentham Science Publishers, 2016)Anti-neoplastic drugs used for cancer treatment often produce damage to healthy cells, leading to severe side effects in patients undergoing chemotherapy. The encapsulation of these agents in nanoparticles reduces the ... -
Dual-Targeting and Stimuli-Triggered Liposomal Drug Delivery in Cancer Treatment
(American Chemical Society, 2021)The delivery of chemotherapeutics to solid tumors using smart drug delivery systems (SDDSs) takes advantage of the unique physiology of tumors (i.e., disordered structure, leaky vasculature, abnormal extracellular matrix ... -
Effect of High-Frequency Ultrasound on Targeted Liposomes
(American Scientific Publishers, 2022)Delivering highly toxic drugs inside a safe carrier to tumors while achieving a controlled and effective drug release at the targeted sites represents an attractive approach to enhance drug efficiency while reducing its ... -
The effect of pegylation and targeting moieties on the ultrasound-mediated drug release from liposomes
(ACS Publications, 2019)The use of targeted liposomes encapsulating chemotherapy drugs enhances the specific targeting of cancer cells, thus, reducing the side effects of these agents and providing a more patient-friendly treatment. Targeted ... -
Effect of pH, ultrasound frequency and power density on the release of calcein from stealth liposomes
(De Gruyter, 2016)The use of liposomes as carriers for chemotherapeutic agents in combination with ultrasound as a stimulus to control the time and space of the drug release is a promising approach for cancer treatment, as it can reduce the ... -
Effect of phospholipid head group on ultrasound‑triggered drug release and cellular uptake of immunoliposomes
(Nature, 2023)Liposomes are the most successful nanoparticles used to date to load and deliver chemotherapeutic agents to cancer cells. They are nano-sized vesicles made up of phospholipids, and targeting moieties can be added to their ... -
An Effective Anticancer Nano-approach for Melanoma and Breast Cancers Using Annona muricate Gold Nanoparticles
(Acta Scientific, 2021-09)Chemotherapy is preferred for the treatment and management of cancer; however, its efficacy is hindered by the off-target side effects of the currently used synthetic drugs. Thus, anticancer drugs with higher safety and ... -
Efficient Immobilization of a Cadmium Chemosensor in a Thin Film: Generation of a Cadmium Sensor Prototype
(American Chemical Society, 2005)The development of an ion-selective chemosensor for Cd2+ allows generation of a “real-time” sensor. Immobilization of the chemosensor on quartz was achieved in a simple monolayer and in a thin film using a polymer intermediary. ... -
Emulsification Characteristics Using a Dynamic Woven Metal Microscreen Membrane
(MDPI, 2016)An oscillatory emulsification system for the production of oil in water emulsions using a commercially available low-cost woven metal microscreen (WMMS) is investigated. The system allows for independent control of both ... -
Encapsulation and release of calcein from herceptin-conjugated eLiposomes
(Elsevier, 2024-03)Achieving an optimal therapeutic level is crucial in effectively eradicating cancer cells during treatment. However, conventional chemotherapy-associated systemic administration of anticancer agents leads to many side ... -
Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review
(MDPI, 2022)Doxorubicin (DOX) is one of the most widely used anthracycline anticancer drugs due to its high efficacy and evident antitumoral activity on several cancer types. However, its effective utilization is hindered by the adverse ... -
Enhancement of the corrosion resistance of mild steel with femtosecond laser- nanostructuring and CrCoNi medium entropy alloy coating
(Elsevier, 2022)In this work, the corrosion resistance of mild steel surface nanostructured with a femtosecond laser and coated with high corrosion resistant CrCoNi (CCN) medium entropy alloy through magnetron sputtering is studied. ... -
Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging
(MDPI, 2022)The field of cancer theranostics has grown rapidly in the past decade and innovative ‘biosmart’ theranostic materials are being synthesized and studied to combat the fast growth of cancer metastases. While current ... -
Facile Ultrasound-Triggered Release of Calcein and Doxorubicin from Iron-Based Metal-Organic Frameworks
(American Scientific Publishers, 2020)Metal-organic frameworks (MOFs) are promising new nanocarriers with potential use in anticancer drug delivery. However, there is a scarcity of studies on the uptake and release of guest molecules associated with MOF ... -
Factors affecting acoustically triggered release of drugs from polymeric micelles
(Elsevier, 2000)A custom ultrasonic exposure chamber with real-time fluorescence detection was used to measure acoustically-triggered drug release from Pluronic P-105 micelles under continuous wave (CW) or pulsed ultrasound in the frequency ...