Browsing Department of Chemical and Biological Engineering by College/Dept "Sheikh Hamdan Award for Medical Sciences"
Now showing items 1-20 of 30
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Acoustically-Activated Liposomal Nanocarriers to Mitigate the Side Effects of Conventional Chemotherapy with a Focus on Emulsion-Liposomes
(MDPI, 2023)To improve currently available cancer treatments, nanomaterials are employed as smart drug delivery vehicles that can be engineered to locally target cancer cells and respond to stimuli. Nanocarriers can entrap chemotherapeutic ... -
Biodegradable Magnesium Alloys for Biomedical Implants: Properties, Challenges, and Surface Modifications with a Focus on Orthopedic Fixation Repair
(MDPI, 2023-12-19)Biomedical devices made from high-modulus and hardness materials play a critical role in enhancing the quality of life for people with bone-related ailments. While these materials have been successfully used in orthopedic ... -
A Comparative Analysis of Numerical Methods for Solving the Leaky Fire and Integrate Model
(MDPI, 2023)The human nervous system is one of the most complex systems of the human body. Understanding its behavior is crucial in drug discovery and developing medical devices. One approach to understanding such a system is to model ... -
Comprehensive Study of a Diabetes Mellitus Mathematical Model Using Numerical Methods with Stability and Parametric Analysis
(MDPI, 2023-01-04)Diabetes is sweeping the world as a silent epidemic, posing a growing threat to public health. Modeling diabetes is an effective method to monitor the increasing prevalence of diabetes and develop cost-effective strategies ... -
Effect of High-Frequency Ultrasound on Targeted Liposomes
(American Scientific Publishers, 2022)Delivering highly toxic drugs inside a safe carrier to tumors while achieving a controlled and effective drug release at the targeted sites represents an attractive approach to enhance drug efficiency while reducing its ... -
Effect of phospholipid head group on ultrasound‑triggered drug release and cellular uptake of immunoliposomes
(Nature, 2023)Liposomes are the most successful nanoparticles used to date to load and deliver chemotherapeutic agents to cancer cells. They are nano-sized vesicles made up of phospholipids, and targeting moieties can be added to their ... -
Encapsulation and release of calcein from herceptin-conjugated eLiposomes
(Elsevier, 2024-03)Achieving an optimal therapeutic level is crucial in effectively eradicating cancer cells during treatment. However, conventional chemotherapy-associated systemic administration of anticancer agents leads to many side ... -
Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review
(MDPI, 2022)Doxorubicin (DOX) is one of the most widely used anthracycline anticancer drugs due to its high efficacy and evident antitumoral activity on several cancer types. However, its effective utilization is hindered by the adverse ... -
Gold-Nanoparticle Hybrid Nanostructures for Multimodal Cancer Therapy
(MDPI, 2022)With the urgent need for bio-nanomaterials to improve the currently available cancer treatments, gold nanoparticle (GNP) hybrid nanostructures are rapidly rising as promising multimodal candidates for cancer therapy. Gold ... -
In Vitro Evaluation of Ultrasound Effectiveness in Controlling Doxorubicin Release from Albumin-Conjugated Liposomes
(American Scientific Publishers, 2022)Functionalized liposomes are among the most promising antineoplastic agents delivery vehicles. Contemporaneous to their accretion at the tumor site, they need to be potentiated to release their cargo using a suitable ... -
Incorporating nanoparticles in 3D printed scaffolds for bone cancer therapy
(Elsevier, 2023)The low occurrence rate of bone cancer contributes to delayed diagnosis and treatment; in addition, the surgical resection of bone tumors can cause significant bone defects, further hindering the effective treatment of the ... -
The Kinetics of Calcein Release from Mixed Targeted Liposomes Using Ultrasound
(American Scientific Publishers, 2022)Site-specific delivery of chemotherapeutics using actively targeted-stimuli-responsive liposomes is a promising approach to enhance the therapeutic efficiency of anti-cancer drugs while reducing the associated undesirable ... -
Liposomal Encapsulation of Chemotherapeutics Agents Combined with the Use of Ultrasound in Cancer Treatment
(American Scientific Publishers, 2023-07)Ultrasound (US) has numerous uses in the medical field, including imaging, tumor ablation, and lithotripsy; another interesting application of US in cancer therapy is as an external trigger in targeted drug delivery. ... -
Liposomes for the Treatment of Brain Cancer — A Review
(MDPI, 2023-06-25)Due to their biocompatibility, non-toxicity, and surface-conjugation capabilities, liposomes are effective nanocarriers that can encapsulate chemotherapeutic drugs and facilitate targeted delivery across the blood–brain ... -
Modeling of the In Vitro Release Kinetics of Sonosensitive Targeted Liposomes
(MDPI, 2022-12-05)Targeted liposomes triggered by ultrasound are a promising drug delivery system as they potentially improve the clinical outcomes of chemotherapy while reducing associated side effects. In this work, a comprehensive model ... -
Modeling the Effects of Chemotherapy and Immunotherapy on Tumor Growth
(American Scientific Publishers, 2021)Mathematical modeling has been used to simulate the interaction of chemotherapy and immunotherapy drugs intervention with the dynamics of tumor cells growth. This work studies the interaction of cells in the immune system, ... -
pH-Responsive Nanocarriers in Cancer Therapy
(MDPI, 2022)A number of promising nano-sized particles (nanoparticles) have been developed to conquer the limitations of conventional chemotherapy. One of the most promising methods is stimuli-responsive nanoparticles because they ... -
Photo-Induced Drug Release from Polymeric Micelles and Liposomes: Phototriggering Mechanisms in Drug-Delivery Systems
(MDPI, 2022)Chemotherapeutic drugs are highly effective in treating cancer. However, the side effects associated with this treatment lower the quality of life of cancer patients. Smart nanocarriers are able to encapsulate these drugs ... -
Recent Advances in Nanoparticle-Based Co-Delivery Systems for Cancer Therapy
(MDPI, 2022-08)Cancer therapies have advanced tremendously throughout the last decade, yet multiple factors still hinder the success of the different cancer therapeutics. The traditional therapeutic approach has been proven insufficient ... -
Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
(MDPI, 2023)Cancer is one of the leading causes of death worldwide. Because each person’s cancer may be unique, diagnosing and treating cancer is challenging. Advances in nanomedicine have made it possible to detect tumors and quickly ...