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Ultrasound-Mediated Drug Delivery in Cancer Therapy: A Review
(American Scientific Publishers, 2020)
The use of ultrasound as a medical diagnostic tool began in the 1940s. Ever since, the medical applications of ultrasound have included imaging, tumor ablation, and lithotripsy; however, an ever-increasing body of literature ...
Parametric Study of a Single Effect Lithium Bromide-Water Absorption Chiller Powered by a Renewable Heat Source
(SDEWES, 2020)
This work investigates the performance of a single-effect absorption chiller utilizing an aqueous lithium bromide solution as the working fluid and driven by hot fluid rejected from either a geothermal power plant or the ...
Thermal Conductivities of Choline Chloride-Based Deep Eutectic Solvents and Their Mixtures with Water: Measurement and Estimation
(MDPI, 2020)
The thermal conductivities of selected deep eutectic solvents (DESs) were determined using the modified transient plane source (MTPS) method over the temperature range from 295 K to 363 K at atmospheric pressure. The results ...
Recent Advances in Metal-Organic Frameworks as Anticancer Drug Delivery Systems: A Review
(Bentham, 2021)
Background: Metal-organic frameworks (MOFs), as attractive hybrid crystalline porous materials, are increasingly being investigated in biomedical applications owing to their exceptional properties, including high porosity, ...
Identification of Novel MicroRNAs as Promising Therapeutics for SARS-CoV-2 by Regulating the EGFR-ADAM17 Axis: An In Silico Analysis
(American Chemical Society, 2021)
Cancer patients contracting SARS-CoV-2 encounter additional challenges due to inflammatory bursts and lymphopenia, which may aggravate breast cancer prognosis. In this in-silico analysis, we identified the potential of ...
Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis
(American Chemical Society, 2021)
In this study, we investigated the interactions between SARS-CoV-2 and miRNAs associated with lung cancer using bioinformatic approaches. A special focus was placed on TMPRSS2 and lung cancer progression pathways involving ...
A Comprehensive Review on Membrane Fouling: Mathematical Modelling, Prediction, Diagnosis, and Mitigation
(MDPI, 2021)
Membrane-based separation has gained increased popularity over the past few decades, particularly reverse osmosis (RO). A major impediment to the improved performance of membrane separation processes, in general, is membrane ...
Transferrin‑modifed liposomes triggered with ultrasound to treat HeLa cells
(Nature, 2021)
Targeted liposomes are designed to target specific receptors overexpressed on the surfaces of cancer cells. This technique ensures site-specific drug delivery to reduce undesirable side effects while enhancing the efficiency ...
Dual-Targeting and Stimuli-Triggered Liposomal Drug Delivery in Cancer Treatment
(American Chemical Society, 2021)
The delivery of chemotherapeutics to solid tumors using smart drug delivery systems (SDDSs) takes advantage of the unique physiology of tumors (i.e., disordered structure, leaky vasculature, abnormal extracellular matrix ...
Modeling of Drug Release Kinetics from Stimuli- Responsive Micelles and Liposomes: A review
(IEEE, 2021)
Nanocarriers such as micelles and liposomes were developed to enhance the delivery of therapeutic drugs to tumors. Internal or external stimuli can be applied to achieve spatiotemporal controlled release from these carriers. ...