Browsing by Subject "Cancer"
Now showing items 21-35 of 35
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Multi-Model Investigation and Adaptive Estimation of the Acoustic Release of a Model Drug From Liposomes
(IEEE, 2019)This paper researches a suitable mathematical model that can reliably predict the release of a model drug (namely calcein) from biologically targeted liposomal nanocarriers triggered by ultrasound. Using mathematical models, ... -
pH-Responsive Nanocarriers in Cancer Therapy
(MDPI, 2022)A number of promising nano-sized particles (nanoparticles) have been developed to conquer the limitations of conventional chemotherapy. One of the most promising methods is stimuli-responsive nanoparticles because they ... -
Preparation of albumin-targeted liposomes and the study of their release characteristics using ultrasound
(2016-01)The main objective of this thesis was to investigate the enhancement of drug delivery using targeted liposomes triggered by ultrasound. In this thesis, a thorough literature review on cancer and drug delivery systems ... -
Transferrin-Targeted Liposomes in Glioblastoma Therapy: A Review
(MDPI, 2026-08-26)Glioblastoma (GBM) is a highly aggressive brain tumor, and its treatment is further complicated by the high selectivity of the blood–brain barrier (BBB). The scientific community is urgently seeking innovative and effective ... -
Ultrasonic-Activated Micellar Drug Delivery for Cancer Treatment
(Wiley InterSciences, 2008)The use of nanoparticles and ultrasound in medicine continues to evolve. Great strides have been made in the areas of producing micelles, nanoemulsions, and solid nanoparticles that can be used in drug delivery. An effective ... -
Ultrasound Triggered Release of Estrone- Targeted Liposomes
(2017-05)The fight against cancer has proven to be a lengthy one. Conventional treatment of cancer usually involves chemotherapy, a therapy known for its detrimental side effects. Doxorubicin, a cytotoxic anthracycline antibiotic, ... -
Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer
(2018-12)Cancer is one of the deadliest diseases in this era. Since conventional treatment has many side effects, its use is limited, which augments the need for new smart drug delivery systems, such as nanocarriers, capable of ... -
Ultrasound-sensitive cRGD-modified liposomes as a novel drug delivery system
(Taylor & Francis, 2022)Targeted liposomes enable the delivery of encapsulated chemotherapeutics to tumours by targeting specific receptors overexpressed on the surfaces of cancer cells; this helps in reducing the systemic side effects associated ... -
Ultrasound-triggered Immunotherapy for Cancer Treatment: An Update
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Use of Model Predictive Control and Artificial Neural Networks to Optimize the Ultrasonic Release of a Model Drug From Liposomes
(IEEE, 2017)The use of echogenic liposomes to deliver chemotherapeutic agents for cancer treatment has gained wide recognition in the last 20 years. Cancerous cells can develop multiple drug resistance (MDR), in part, due to the drop ... -
The Use of Transferrin and Ultrasound in Cancer Treatment
(2019-05)Site-specific drug delivery represents an attractive approach in cancer treatment to reduce the undesirable side-effects of anticancer therapeutics and increase the accumulation of drugs at tumor sites. Surface modification ... -
The Use of Ultrasound and Micelles in Cancer Treatment
(American Scientific Publishers, 2008)The high toxicity of potent chemotherapeutic drugs like Doxorubicin (Dox) limits the therapeutic window in which they can be applied. This window can be expanded by controlling the drug delivery in both space and time such ... -
Using a Cavitation Model to Represent the Acoustic Release Kinetics from Folated Micelles
(2014-12)Anti-neoplastic drugs used for cancer treatment have various damaging effects on healthy cells, leading to several side effects in patients undergoing chemotherapy. The encapsulation of these agents in nanoparticles, such ... -
Whole Organism Model to Study Molecular Mechanisms of Differentiation and Dedifferentiation
(MDPI, 2020)Cancer recurrence has remained a significant challenge, despite advances in therapeutic approaches. In part, this is due to our incomplete understanding of the biology of cancer stem cells and the underlying molecular ...