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Now showing items 11-20 of 33
Synergistic Nanomedicine: Passive, Active, and Ultrasound-Triggered Drug Delivery in Cancer Treatment
(American Scientific Publishers, 2015)
Nanocarriers are heavily researched as drug delivery vehicles capable of sequestering antineoplastic agents and then releasing their contents at the desired location. The feasibility of using such carriers stems from their ...
Liposomes in Active, Passive and Acoustically-Triggered Drug Delivery
(Bentham Science Publishers, 2019)
Cancer has become one of the most deadly noncommunicable diseases globally. Several modalities used to treat cancer patients exist today yet many have failed to prove high efficacy with low side effects. The most common ...
Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery
(Elsevier, 2010)
Ultrasound (US) increases efficacy of drugs delivered from micelles, but the pharmacokinetics have not been studied previously. In this study, US was used to deliver doxorubicin (Dox) sequestered in micelles in an in vivo ...
Kinetics of acoustic release of doxorubicin from stabilized and unstabilized micelles and the effect of temperature
(Elsevier, 2011)
Ultrasound is being investigated as a trigger mechanism to deliver high concentrations of chemotherapy drugs to cancerous tissues using polymeric micelles. In this paper, we examined the kinetics of acoustic release of ...
Phase transitions of nanoemulsions using ultrasound: Experimental observations
(Elsevier, 2012)
The ultrasound-induced transformation of perfluorocarbon liquids to gases is of interest in the area of drug and gene delivery. In this study, three independent parameters (temperature, size, and perfluorocarbon species) ...
Mathematical modeling of microbubble cavitation at 70 kHz and the importance of the subharmonic in drug delivery from micelles
(Elsevier, 2013)
In order to gain insight into the experimental observation of ultrasound-induced release of drugs from micelles, we modeled the dynamic oscillations of a 10-μm-diameter bubble insonated at 70 kHz. The Parlitz modification ...
Factors Affecting the Acoustic In Vitro Release of Calcein from PEGylated Liposomes
(American Scientific Publishers, 2019)
Typical methods used in cancer treatment, including chemotherapy, are debilitating because of the various adverse side effects experienced by cancer patients. The free drug injected into the patient at given doses affects ...
Preliminary Results of Combining Low Frequency Low Intensity Ultrasound and Liposomal Drug Delivery to Treat Tumors in Rats
(American Scientific Publishers, 2011)
Ultrasound is a convenient trigger for site-specific drug delivery in cancer therapy. Nanosized liposomes formulated from soy phosphatidyl choline, cholesterol, 1,2-distearoyl-sn-glycero- 3-phosphoethanolamine-N-[carboxy ...
Review on Triggered Liposomal Drug Delivery with a Focus on Ultrasound
(Bentham Science Publishers, 2015)
Chemotherapy is widely used for cancer treatment; however, it causes unwanted side effects in patients. To avoid these adverse effects, nanocarriers have been developed, which can be loaded with the chemotherapeutic agents, ...
Comparing microbubble cavitation at 500 kHz and 70 kHz related to micellar drug delivery using ultrasound
(Elsevier, 2013)
We have previously reported that ultrasonic drug release at 70 kHz was found to correlate with the presence of subharmonic emissions. No evidence of drug release or of the subharmonic emissions were detected in experiments ...