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    Improving the Efficacy of Anticancer Drugs via Encapsulation and Acoustic Release

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    56Improving Chemotherapy(CTMC).pdf (1.290Mb)
    Date
    2018
    Author
    Ahmed, Salma E.
    Awad, Nahid S.
    Paul, Vinod
    Moussa, Hesham Gamal
    Husseini, Ghaleb
    Advisor(s)
    Unknown advisor
    Type
    Peer-Reviewed
    Article
    Postprint
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    Abstract
    Conventional chemotherapeutics lack the specificity and controllability, thus may poison healthy cells while attempting to kill cancerous ones. Newly developed nano-drug delivery systems have shown promise in delivering anti-tumor agents with enhanced stability, durability and overall performance; especially when used along with targeting and triggering techniques. This work traces back the history of chemotherapy, addressing the main challenges that have encouraged the medical researchers to seek a sanctuary in nanotechnological-based drug delivery systems that are grafted with appropriate targeting techniques and drug release mechanisms. A special focus will be directed to acoustically triggered liposomes encapsulating doxorubicin.
    DSpace URI
    http://hdl.handle.net/11073/21319
    External URI
    https://doi.org/10.2174/1568026618666180608125344
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