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Targeting Breast Cancer Using Hyaluronic Acid-Conjugated Liposomes Triggered with Ultrasound
(American Science Publishers, 2021)
The successful targeting of tumors can be achieved by conjugating targeting moieties to nanoparticles. These modifications allow nannocarriers to achieve greater targeting specificity through binding to specific receptors ...
Recent Advances in Metal-Organic Frameworks as Anticancer Drug Delivery Systems: A Review
(Bentham, 2021)
Background: Metal-organic frameworks (MOFs), as attractive hybrid crystalline porous materials, are increasingly being investigated in biomedical applications owing to their exceptional properties, including high porosity, ...
Identification of Novel MicroRNAs as Promising Therapeutics for SARS-CoV-2 by Regulating the EGFR-ADAM17 Axis: An In Silico Analysis
(American Chemical Society, 2021)
Cancer patients contracting SARS-CoV-2 encounter additional challenges due to inflammatory bursts and lymphopenia, which may aggravate breast cancer prognosis. In this in-silico analysis, we identified the potential of ...
Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis
(American Chemical Society, 2021)
In this study, we investigated the interactions between SARS-CoV-2 and miRNAs associated with lung cancer using bioinformatic approaches. A special focus was placed on TMPRSS2 and lung cancer progression pathways involving ...
A Comprehensive Review on Membrane Fouling: Mathematical Modelling, Prediction, Diagnosis, and Mitigation
(MDPI, 2021)
Membrane-based separation has gained increased popularity over the past few decades, particularly reverse osmosis (RO). A major impediment to the improved performance of membrane separation processes, in general, is membrane ...
Transferrin‑modifed liposomes triggered with ultrasound to treat HeLa cells
(Nature, 2021)
Targeted liposomes are designed to target specific receptors overexpressed on the surfaces of cancer cells. This technique ensures site-specific drug delivery to reduce undesirable side effects while enhancing the efficiency ...
Dual-Targeting and Stimuli-Triggered Liposomal Drug Delivery in Cancer Treatment
(American Chemical Society, 2021)
The delivery of chemotherapeutics to solid tumors using smart drug delivery systems (SDDSs) takes advantage of the unique physiology of tumors (i.e., disordered structure, leaky vasculature, abnormal extracellular matrix ...
Modeling of Drug Release Kinetics from Stimuli- Responsive Micelles and Liposomes: A review
(IEEE, 2021)
Nanocarriers such as micelles and liposomes were developed to enhance the delivery of therapeutic drugs to tumors. Internal or external stimuli can be applied to achieve spatiotemporal controlled release from these carriers. ...
An Effective Anticancer Nano-approach for Melanoma and Breast Cancers Using Annona muricate Gold Nanoparticles
(Acta Scientific, 2021-09)
Chemotherapy is preferred for the treatment and management of cancer; however, its efficacy is hindered by the off-target side effects of the currently used synthetic drugs. Thus, anticancer drugs with higher safety and ...
Ultrasound-Triggered Liposomes Encapsulating Quantum Dots as Safe Fluorescent Markers for Colorectal Cancer
(MDPI, 2021)
Quantum dots (QDs) are a promising tool to detect and monitor tumors. However, their small size allows them to accumulate in large quantities inside the healthy cells (in addition to the tumor cells), which increases their ...